EZH2 mutational status predicts poor survival in myelofibrosis.
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Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learnedThe Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and OpportunitiesEZH2 in normal hematopoiesis and hematological malignanciesGenetics of myeloproliferative neoplasmsChromatin targeting drugs in cancer and immunityStructural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET DomainWeaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In VitroLoss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.Myeloid neoplasias: what molecular analyses are telling usImmunomodulatory agents in myelofibrosis.Array comparative genomic hybridization and sequencing of 23 genes in 80 patients with myelofibrosis at chronic or acute phaseSurvival and prognosis among 1545 patients with contemporary polycythemia vera: an international study.Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosisCurrent outlook on molecular pathogenesis and treatment of myeloproliferative neoplasms.EZH2 in normal and malignant hematopoiesis.JAK2 V617F genotype is a strong determinant of blast transformation in primary myelofibrosis.CD133 marks a stem cell population that drives human primary myelofibrosis.Polycomb repressive complex 2 is required for MLL-AF9 leukemiaA complex Polycomb issue: the two faces of EZH2 in cancer.One thousand patients with primary myelofibrosis: the mayo clinic experience.Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic LeukemiaNew Strategies in Myeloproliferative Neoplasms: The Evolving Genetic and Therapeutic Landscape.Perspectives and future directions for epigenetics in hematology.Loss of Ezh2 cooperates with Jak2V617F in the development of myelofibrosis in a mouse model of myeloproliferative neoplasm.The future of epigenetic therapy in solid tumours--lessons from the past.Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosisEpigenetics of hematopoiesis and hematological malignancies.Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms.Primary myelofibrosis: 2012 update on diagnosis, risk stratification, and management.Disordered epigenetic regulation in the pathophysiology of myeloproliferative neoplasms.Mutations in ASXL1 are associated with poor prognosis across the spectrum of malignant myeloid diseases.Janus kinase inhibition and its effect upon the therapeutic landscape for myelofibrosis: from palliation to cure?BCR-ABL1-negative chronic myeloid neoplasms: an update on management techniques.Allogeneic hematopoietic cell transplantation for myelofibrosis in the era of JAK inhibitors.Emerging targeted therapies in myelofibrosis.Myeloproliferative neoplasm animal modelsHematopoietic stem cells, progenitor cells and leukemic stem cells in adult myeloproliferative neoplasms.Epigenetic alterations in hematopoietic malignancies.Molecular biology of Philadelphia-negative myeloproliferative neoplasmsThe ASXL-BAP1 axis: new factors in myelopoiesis, cancer and epigenetics.
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P2860
EZH2 mutational status predicts poor survival in myelofibrosis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
EZH2 mutational status predicts poor survival in myelofibrosis.
@en
EZH2 mutational status predicts poor survival in myelofibrosis.
@nl
type
label
EZH2 mutational status predicts poor survival in myelofibrosis.
@en
EZH2 mutational status predicts poor survival in myelofibrosis.
@nl
prefLabel
EZH2 mutational status predicts poor survival in myelofibrosis.
@en
EZH2 mutational status predicts poor survival in myelofibrosis.
@nl
P2093
P50
P1433
P1476
EZH2 mutational status predicts poor survival in myelofibrosis
@en
P2093
Alessandro M Vannucchi
Amy V Jones
Andreas Reiter
Andrew Duncombe
Claire Hidalgo-Curtis
Flavia Biamonte
Francisco Cervantes
Giovanni Barosi
Joannah Score
Katerina Zoi
P304
P356
10.1182/BLOOD-2011-06-363424
P407
P577
2011-09-14T00:00:00Z