Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo.
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Regulation of Fc∈RI signaling in mast cells by G protein-coupled receptor kinase 2 and its RH domain.Getting Syk: spleen tyrosine kinase as a therapeutic target.Spleen tyrosine kinase inhibition attenuates autoantibody production and reverses experimental autoimmune GN.A novel model of IgE-mediated passive pulmonary anaphylaxis in rats.Signal transduction and chemotaxis in mast cellsSyk Regulates Neutrophilic Airway Hyper-Responsiveness in a Chronic Mouse Model of Allergic Airways Inflammation.Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1.The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia.In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signalingSpleen tyrosine kinase inhibitors: a review of the patent literature 2010 - 2013.Spleen Tyrosine Kinase Modulates Fibrous Airway Obliteration and Associated Lymphoid Neogenesis After Transplantation.PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy VolunteersBI 1002494, a Novel Potent and Selective Oral Spleen Tyrosine Kinase Inhibitor, Displays Differential Potency in Human Basophils and B Cells.Spleen tyrosine kinase inhibition blocks airway constriction and protects from Th2-induced airway inflammation and remodeling.LC3-Associated Phagocytosis Is Required for Dendritic Cell Inflammatory Cytokine Response to Gut Commensal Yeast Saccharomyces cerevisiae.Syk mediates airway contractility independent of leukocyte function.Myeloid cell-mediated renal injury in rapidly progressive glomerulonephritis depends upon spleen tyrosine kinase.Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis.Role of the Spleen Tyrosine Kinase Pathway in Driving Inflammation in IgA Nephropathy
P2860
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P2860
Induced Syk deletion leads to suppressed allergic responses but has no effect on neutrophil or monocyte migration in vivo.
description
2011 nî lūn-bûn
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2011年の論文
@ja
2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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name
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@en
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@nl
type
label
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@en
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@nl
prefLabel
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@en
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@nl
P2093
P2860
P356
P1476
Induced Syk deletion leads to ...... or monocyte migration in vivo.
@en
P2093
Andreas Schnapp
Birgit E Stierstorfer
Florian Gantner
Klaus J Erb
Lutz Wollin
Matthias J Duechs
Thierry Bouyssou
P2860
P304
P356
10.1002/EJI.201141502
P407
P577
2011-09-26T00:00:00Z