From growing to secreting: new roles for mTOR in aging cells.
about
Caloric restriction: is mammalian life extension linked to p53?Advances in targeting signal transduction pathwaysBig mice die young but large animals live longerElimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycinContact inhibition and high cell density deactivate the mammalian target of rapamycin pathway, thus suppressing the senescence programRas/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.NCI's provocative questions on cancer: some answers to ignite discussion.Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging.Koschei the immortal and anti-aging drugsHypoxia and gerosuppression: the mTOR saga continuesAnswering the ultimate question "what is the proximal cause of aging?"Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes.Common drugs and treatments for cancer and age-related diseases: revitalizing answers to NCI's provocative questions.Rat retinal transcriptome: effects of aging and AMD-like retinopathyComparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.M(o)TOR of aging: MTOR as a universal molecular hypothalamusRapamycin extends life- and health span because it slows aging.CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and MTOR activity determine geroconversion.Shining the Light on Senescence Associated LncRNAs.Evolving paradigms in clinical pharmacology and therapeutics for the treatment of Duchenne muscular dystrophy.While reinforcing cell cycle arrest, rapamycin and Torins suppress senescence in UVA-irradiated fibroblasts.RhoA/ROCK inhibition improves the beneficial effects of glucocorticoid treatment in dystrophic muscle: implications for stem cell depletion.mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome.Hepatocyte senescence in vivo following preconditioning for liver repopulation.[Cellular senescence and the myth of Janus].
P2860
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P2860
From growing to secreting: new roles for mTOR in aging cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
From growing to secreting: new roles for mTOR in aging cells.
@en
From growing to secreting: new roles for mTOR in aging cells.
@nl
type
label
From growing to secreting: new roles for mTOR in aging cells.
@en
From growing to secreting: new roles for mTOR in aging cells.
@nl
prefLabel
From growing to secreting: new roles for mTOR in aging cells.
@en
From growing to secreting: new roles for mTOR in aging cells.
@nl
P356
P1433
P1476
From growing to secreting: new roles for mTOR in aging cells
@en
P2093
Giovambattista Pani
P304
P356
10.4161/CC.10.15.16886
P50
P577
2011-08-01T00:00:00Z