Agonist-independent modulation of N-type calcium channels by ORL1 receptors. - Wikidata - awgldk - TriplyDB

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

http://www.wikidata.org/entity/Q54733725

about

Functional plasticity of the N/OFQ-NOP receptor system determines analgesic properties of NOP receptor agonists Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis In vivo silencing of the Ca(V)3.2 T-type calcium channels in sensory neurons alleviates hyperalgesia in rats with streptozocin-induced diabetic neuropathy.MacMARCKS interacts with the metabotropic glutamate receptor type 7 and modulates G protein-mediated constitutive inhibition of calcium channels.Modulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons.Modulation of pain transmission by G-protein-coupled receptors.The immediately releasable pool of mouse chromaffin cell vesicles is coupled to P/Q-type calcium channels via the synaptic protein interaction site.G protein modulation of CaV2 voltage-gated calcium channels Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid-mediated cAMP overshoot.In vivo opioid receptor heteromerization: where do we stand?Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking β-arrestin 2 Novel splice variants of rat CaV2.1 that lack much of the synaptic protein interaction site are expressed in neuroendocrine cells Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.Neuronal calcium channels: splicing for optimal performance.Regulation of Ca(V)2 calcium channels by G protein coupled receptors.Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.Cellular mechanisms of nociceptin/orphanin FQ (N/OFQ) peptide (NOP) receptor regulation and heterologous regulation by N/OFQ.Coupling specificity of NOP opioid receptors to pertussis-toxin-sensitive Galpha proteins in adult rat stellate ganglion neurons using small interference RNA The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes Supramolecular assemblies and localized regulation of voltage-gated ion channels.Calcium channel functions in pain processing Signaling complexes of voltage-gated calcium channels Trafficking and stability of voltage-gated calcium channels.Opioid receptor targeting ligands for pain management: a review and update.Calcium-permeable ion channels in pain signaling.Pharmacological characterization of inhibitory effects of postsynaptic opioid and cannabinoid receptors on calcium currents in neonatal rat nucleus tractus solitarius Subtype-specific reduction of voltage-gated calcium current in medium-sized dorsal root ganglion neurons after painful peripheral nerve injury.Heterodimerization of ORL1 and opioid receptors and its consequences for N-type calcium channel regulation.Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.Prolonged AT1R activation induces CaV1.2 channel internalization in rat cardiomyocytes.Modulation of Ca2+ channels by heterologously expressed wild-type and mutant human micro-opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism.Opioid-related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N-type calcium channels.Constitutive activity of the Ghrelin receptor reduces surface expression of voltage-gated Ca2+ channels in a CaVβ-dependent manner.The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells.The nociceptin receptor inhibits axonal regeneration and recovery from spinal cord injury.Inhibitory Gi/O-coupled receptors in somatosensory neurons: Potential therapeutic targets for novel analgesics.Dopamine-mediated calcium channel regulation in synaptic suppression in L. stagnalis interneurons.

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Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

http://www.wikidata.org/entity/Q54733725

description

2004 nî lūn-bûn

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@en

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@nl

type

label

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@en

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@nl

prefLabel

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@en

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@nl

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Nature Neuroscience

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Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

@en

P2093

Christian Barrere

http://www.w3.org/2001/XMLSchema#string

Christophe Altier

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Clinton J Doering

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Emmanuel Bourinet

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Jawed Hamid

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Joel Nargeot

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John E McRory

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Olivier Poirot

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P2860

G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclase

Direct binding of G-protein betagamma complex to voltage-dependent calcium channels

A critical protein kinase C phosphorylation site on the 5-HT(1A) receptor controlling coupling to N-type calcium channels

Nociceptin inhibits calcium channel currents in a subpopulation of small nociceptive trigeminal ganglion neurons in mouse

Control of glutamate and GABA release by nociceptin/orphanin FQ in the rat lateral amygdala

A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2

Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel

Expression of voltage-gated Ca2+ channel subtypes in cultured astrocytes

Differential modulation of N-type 1B and P/Q-type 1A calcium channels by different G protein subunit isoforms

The role of the ORL1 receptor in the modulation of spinal neurotransmission by nociceptin/orphanin FQ and nocistatin.

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P304

118-125

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scholarly article

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10.1038/NN1180

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P433

2

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7

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Gerald W. Zamponi

Aaron M. Beedle

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2004-01-18T00:00:00Z

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8914407

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1044957817

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14730309

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