Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells.
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Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewalIdentification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastomaCytokines inducing bone marrow SCA+ cells migration into pancreatic islet and conversion into insulin-positive cells in vivo.Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions.Human fetal liver stromal cells that overexpress bFGF support growth and maintenance of human embryonic stem cellsFetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells.Components of the hematopoietic compartments in tumor stroma and tumor-bearing miceLis1 is required for the expansion of hematopoietic stem cells in the fetal liver.Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesisAngiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cellsThe distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells.The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.Robust in vivo transduction of nervous system and neural stem cells by early gestational intra amniotic gene transfer using lentiviral vector.Angiopoietin-like protein 3 supports the activity of hematopoietic stem cells in the bone marrow niche.Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line.Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.IGF-IR determines the fates of BCR/ABL leukemia.IGF binding protein 2 supports the survival and cycling of hematopoietic stem cellsOntogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factorA MEK inhibitor abrogates myeloproliferative disease in Kras mutant mice.Murine hematopoietic stem cells change their surface phenotype during ex vivo expansionPRC2 inhibition counteracts the culture-associated loss of engraftment potential of human cord blood-derived hematopoietic stem and progenitor cells.Novel chemical attempts at ex vivo hematopoietic stem cell expansion.The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironmentMouse lysocardiolipin acyltransferase controls the development of hematopoietic and endothelial lineages during in vitro embryonic stem-cell differentiation.The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjectionATF4 plays a pivotal role in the development of functional hematopoietic stem cells in mouse fetal liver.Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in DrosophilaAngiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantationHematopoietic stem cells: the paradigmatic tissue-specific stem cell.Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor riskGlypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance.In vivo and in vitro differentiation of uniparental embryonic stem cells into hematopoietic and neural cell typesMesenchymal stem cells as therapeutics.IGF ligand and receptor regulation of mammary development
P2860
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P2860
Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@en
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@nl
type
label
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@en
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@nl
prefLabel
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@en
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@nl
P1433
P1476
Insulin-like growth factor 2 e ...... for hematopoietic stem cells.
@en
P2093
Cheng Cheng Zhang
P304
P356
10.1182/BLOOD-2003-08-2955
P407
P577
2003-10-30T00:00:00Z