Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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Role of Cytochrome P450 Enzymes in the Metabolic Activation of Tyrosine Kinase Inhibitors Metabolism and Bioactivation of Corynoline With Characterization of the Glutathione/Cysteine Conjugate and Evaluation of Its Hepatotoxicity in Mice

P2860

Q58788266-EE319560-43D3-4CFD-AA5C-7C8A2A5227C0 Q59136455-161EC898-43FF-4F53-9F3A-B7DA46FFF8D9

P2860

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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http://www.wikidata.org/entity/Q54977664

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

@wuu

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

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2018年學術文章

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2018年學術文章

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name

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

@en

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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type

Item

label

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

@en

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib

@en

prefLabel

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

@en

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

@nl

P1476

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib

@en

P2093

Arsany A Abouda

http://www.w3.org/2001/XMLSchema#string

David S Bourgeois

http://www.w3.org/2001/XMLSchema#string

Gracia M Amaya

http://www.w3.org/2001/XMLSchema#string

James A Perkins

http://www.w3.org/2001/XMLSchema#string

Kahari J Wines

http://www.w3.org/2001/XMLSchema#string

Mohamed Mohamud

http://www.w3.org/2001/XMLSchema#string

Rebecca Durandis

http://www.w3.org/2001/XMLSchema#string

Samuel A Starks

http://www.w3.org/2001/XMLSchema#string

P2860

Pharmacogenetic pathway analysis for determination of sunitinib-induced toxicity.

Important role of CYP2J2 in protein kinase inhibitor degradation: a possible role in intratumor drug disposition and resistance

Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer.

Role of the lean body mass and of pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of sunitinib in cancer patients.

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis.

Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib.

Cytochrome P450-mediated bioactivation of the epidermal growth factor receptor inhibitor erlotinib to a reactive electrophile

Role of biotransformation in drug-induced toxicity: influence of intra- and inter-species differences in drug metabolism.

Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib

Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients.

P304

570-584

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P31

scholarly article

P356

10.1021/ACS.CHEMRESTOX.8B00005

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

R Nathan Daniels

Klarissa D Jackson

P577

2018-06-18T00:00:00Z

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P698

29847931

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P932

6108078

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Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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P2860

P2860

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib.

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name

type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932