Knockout rats generated by embryo microinjection of TALENs. - Wikidata - awgldk - TriplyDB

Knockout rats generated by embryo microinjection of TALENs.

Knockout rats generated by embryo microinjection of TALENs.

http://www.wikidata.org/entity/Q55054726

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Less is more: strategies to remove marker genes from transgenic plants Generation of TALEN-mediated GRdim knock-in rats by homologous recombination Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes Genome-scale engineering for systems and synthetic biology Targeting DNA With Fingers and TALENs Precision editing of large animal genomes Genome Engineering with TALE and CRISPR Systems in Neuroscience Large animal models of cardiovascular disease Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Use of genetically-engineered pig donors in islet transplantation Rat embryonic stem cells create new era in development of genetically manipulated rat models Genome-editing tools for stem cell biology Clinical lung xenotransplantation--what donor genetic modifications may be necessary?Rat placentation: an experimental model for investigating the hemochorial maternal-fetal interface Transcription activator-like effectors: a toolkit for synthetic biology Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond Making designer mutants in model organisms Quantifying on- and off-target genome editing Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy Simple Genome Editing of Rodent Intact Embryos by Electroporation Genome editing: the road of CRISPR/Cas9 from bench to clinic Mutagenesis and phenotyping resources in zebrafish for studying development and human disease Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering Knockout of the adp gene related with colonization in Bacillus nematocida B16 using customized transcription activator-like effectors nucleases.TALENoffer: genome-wide TALEN off-target prediction.Generation of Esr1-knockout rats using zinc finger nuclease-mediated genome editing.A robust TALENs system for highly efficient mammalian genome editing.Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity An improved Red/ET recombineering system and mouse ES cells culture conditions for the generation of targeted mutant mice.Targeted gene disruption in zebrafish reveals noncanonical functions of LH signaling in reproduction TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges.TALEN-mediated genetic tailoring as a tool to analyze the function of acquired mutations in multiple myeloma cells Cell cycle synchronization of leukemia inhibitory factor (LIF)-dependent porcine-induced pluripotent stem cells and the generation of cloned embryos.Generation of myostatin B knockout yellow catfish (Tachysurus fulvidraco) using transcription activator-like effector nucleases Next-generation mammalian genetics toward organism-level systems biology

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Knockout rats generated by embryo microinjection of TALENs.

http://www.wikidata.org/entity/Q55054726

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

Knockout rats generated by embryo microinjection of TALENs.

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Knockout rats generated by embryo microinjection of TALENs.

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type

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Knockout rats generated by embryo microinjection of TALENs.

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Knockout rats generated by embryo microinjection of TALENs.

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Knockout rats generated by embryo microinjection of TALENs.

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Knockout rats generated by embryo microinjection of TALENs.

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Nature Biotechnology

P1476

Knockout rats generated by embryo microinjection of TALENs.

@en

P2093

Anna I Vincent

http://www.w3.org/2001/XMLSchema#string

Brett J Niles

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Claire Usal

http://www.w3.org/2001/XMLSchema#string

Elo Leung

http://www.w3.org/2001/XMLSchema#string

Ignacio Anegon

http://www.w3.org/2001/XMLSchema#string

Laurent Tesson

http://www.w3.org/2001/XMLSchema#string

Séverine Ménoret

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Séverine Remy

http://www.w3.org/2001/XMLSchema#string

Xiangdong Meng

http://www.w3.org/2001/XMLSchema#string

Yolanda Santiago

http://www.w3.org/2001/XMLSchema#string

P2860

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

Targeting DNA double-strand breaks with TAL effector nucleases

De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks

Knockout rats via embryo microinjection of zinc-finger nucleases

Targeted genome editing across species using ZFNs and TALENs

A simple cipher governs DNA recognition by TAL effectors

Breaking the code of DNA binding specificity of TAL-type III effectors

Targeted integration in rat and mouse embryos with zinc-finger nucleases

A TALE nuclease architecture for efficient genome editing

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

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695-696

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scholarly article

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10.1038/NBT.1940

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8

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29

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Philip D Gregory

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2011-08-05T00:00:00Z

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51552697

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1051218365

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21822240

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