about
The human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding proteinTBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescenceEAPP, a novel E2F binding protein that modulates E2F-dependent transcriptionARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stressThe balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cellsImmortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathwayp14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activityA novel ARF-binding protein (LZAP) alters ARF regulation of HDM2The novel ETS factor TEL2 cooperates with Myc in B lymphomagenesisCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseTwist is a potential oncogene that inhibits apoptosisp53-independent functions of the p19(ARF) tumor suppressorPERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 familyThe E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complexTopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survivalShuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformationE2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferasesRibosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathwayE2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpointsIdentification of E-box factor TFE3 as a functional partner for the E2F3 transcription factorE2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loopRegulation of E2F1 by BRCT domain-containing protein TopBP1Selection of novel mediators of E2F1-induced apoptosis through retroviral expression of an antisense cDNA library(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.Molecular substratification of bladder cancer: moving towards individualized patient managementTo live or let die - complexity within the E2F1 pathwayA role for E2F activities in determining the fate of Myc-induced lymphomagenesisp14 Arf promotes small ubiquitin-like modifier conjugation of Werners helicaseThe INK4 family of cell cycle inhibitors in cancerAssociation of p14ARF with the p120E4F transcriptional repressor enhances cell cycle inhibitionThe T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiatorThe proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylationp73 is over-expressed in vulval cancer principally as the Delta 2 isoformActivation and activities of the p53 tumour suppressor proteinThe proto-oncogene LRF is under post-transcriptional control of MiR-20a: implications for senescenceCHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancerARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathwayArf induction by Tgfβ is influenced by Sp1 and C/ebpβ in opposing directionsOcular expression and distribution of products of the POAG-associated chromosome 9p21 gene region
P2860
Q24291005-F7856284-01A5-4C29-AD17-27A4201FB0FFQ24292042-5C505817-8F78-4A04-84E8-F44A6D02CB1EQ24295046-8A602721-96E9-4870-8987-CBEF78601928Q24296257-FC49989D-B1D2-4F62-8C33-DBCB7D99EC37Q24297086-D69EADA2-9719-4FF3-99D9-BF51D4238541Q24308746-10114CE1-3D89-440E-9D46-EA1BACFCECFFQ24319978-5BEEE70F-2C97-4397-8AF7-EDC122C2AC88Q24328749-35AC09D0-D8FC-4C50-BC7E-27371712D594Q24519077-6168DB69-A7A7-4EAD-A373-6DD4553B6B37Q24554436-553822E2-0FBC-4B91-B222-7AF34B29CB06Q24599468-A6D52030-B209-49F5-B78E-F9D15AFD891EQ24600863-B9840DCB-2EE3-46FC-8639-68EBFDB7B71AQ24608240-35D0C49F-466F-4DA2-A611-C709169FB480Q24624687-96EE59D7-A5C2-48F9-8808-5D8E0350D6C0Q24627319-603D1845-952B-4F93-B65E-E282D98AA438Q24642177-9EC45706-C24F-4A6A-B3A7-937585C8EC6EQ24646412-1EA3AC78-AF2D-47FB-A629-EA7EAEDECB9AQ24648370-52DDEC9F-AE16-47CF-A62D-1CD12C9A1257Q24672780-2489C080-9F2C-460B-B022-E9A0E61D4F9DQ24673143-953389E7-B4A8-4D66-9ECB-123964C76A33Q24674252-41743897-20EE-40C5-9488-D034001C2AD8Q24682764-B00FE047-4D72-4FB7-B665-26BB250ABFEEQ24804591-02C9E4DA-A906-42A7-9029-5B45CB9965B5Q24812998-F6D68458-1BF4-4339-893A-2D9309987ECAQ26744343-0219E81F-C933-4AFF-9535-C51B55ECC1D0Q26862588-99A32CDA-8B19-4C3A-9F4F-914C2BDBD475Q27349135-2E5511C7-F8D8-469A-A825-FDD3456A8F85Q28115495-8CBFA869-BC75-465B-B240-843CE0CED127Q28145080-0036DCBC-0630-48F6-934B-99CC76D53A52Q28215807-7B3B6EBC-42CD-4036-B946-5535D67351D0Q28217021-72854C42-EB81-4B4C-9A6E-1706FF1CF7D6Q28258178-5E8C4F5E-4C82-4207-B2CF-A350D2517566Q28344288-967A8CE6-4722-4D8D-B97E-EE84BEA9CAC0Q28364918-6C760C3C-D095-485F-90D0-F62F3CA179AFQ28366563-EAA424CA-A0D7-46B3-BDDE-42922EA0A306Q28473050-94914B7F-7945-44C1-956D-EF4E1C8A14FCQ28473504-03F5A7D7-BEFB-4660-892E-C627E22C519FQ28506702-C339DA8B-5E06-4516-8776-4F83001C19A6Q28535099-2AA6F519-4A6D-42D6-9AC9-E1AF6FE2EFDDQ28572262-E23C4F6F-0F4E-40E0-A985-FCE98D754AF5
P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
p14ARF links the tumour suppressors RB and p53.
@en
p14ARF links the tumour suppressors RB and p53.
@nl
type
label
p14ARF links the tumour suppressors RB and p53.
@en
p14ARF links the tumour suppressors RB and p53.
@nl
prefLabel
p14ARF links the tumour suppressors RB and p53.
@en
p14ARF links the tumour suppressors RB and p53.
@nl
P2093
P356
P1433
P1476
p14ARF links the tumour suppressors RB and p53.
@en
P2093
Phillips AC
Vousden KH
P2888
P304
P356
10.1038/25867
P407
P577
1998-09-01T00:00:00Z
P6179
1012546516