about
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RASInhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genesChemokine signaling via the CXCR2 receptor reinforces senescenceAn adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.A complex secretory program orchestrated by the inflammasome controls paracrine senescence.High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycleCondensin II mutation causes T-cell lymphoma through tissue-specific genome instabilitySKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.Control of senescence by CXCR2 and its ligands.A role for CXCR2 in senescence, but what about in cancer?Senescence: a new weapon for cancer therapy.Amifostine impairs p53-mediated apoptosis of human myeloid leukemia cells.MGMT Expression Predicts PARP-Mediated Resistance to Temozolomide.Detecting the Senescence-Associated Secretory Phenotype (SASP) by High Content Microscopy Analysis.MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.Senescence impairs successful reprogramming to pluripotent stem cells.p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.Suppression of autophagy impedes glioblastoma development and induces senescence.Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?Paracrine cellular senescence exacerbates biliary injury and impairs regeneration.Premature senescence in cells from patients with autosomal recessive hypercholesterolemia (ARH): evidence for a role for ARH in mitosis.Unbiased Characterization of the Senescence-Associated Secretome Using SILAC-Based Quantitative ProteomicsNuclear pore density controls heterochromatin reorganization during senescenceInhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescenceMeasuring the Inflammasome in Oncogene-Induced SenescenceInhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescenceThe innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotypePHD3 Regulates p53 Protein Stability by Hydroxylating Proline 359The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Juan Carlos Acosta
@ast
Juan Carlos Acosta
@en
Juan Carlos Acosta
@es
Juan Carlos Acosta
@nl
Juan Carlos Acosta
@sl
type
label
Juan Carlos Acosta
@ast
Juan Carlos Acosta
@en
Juan Carlos Acosta
@es
Juan Carlos Acosta
@nl
Juan Carlos Acosta
@sl
prefLabel
Juan Carlos Acosta
@ast
Juan Carlos Acosta
@en
Juan Carlos Acosta
@es
Juan Carlos Acosta
@nl
Juan Carlos Acosta
@sl
P106
P21
P31
P496
0000-0002-7989-7329