mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
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"Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 DiabetesRNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescenceIdentification of Salvia haenkei as gerosuppressant agent by using an integrated senescence-screening assayZinc finger protein ZFP36L1 promotes osteoblastic differentiation but represses adipogenic differentiation of mouse multipotent cellsRapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanismPotency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing.Mitochondria are required for pro-ageing features of the senescent phenotype.Directed elimination of senescent cells by inhibition of BCL-W and BCL-XLFrom Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence.Ionizing Radiation-Induced Endothelial Cell Senescence and Cardiovascular Diseases.A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses.Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosisEstablishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.Shining the Light on Senescence Associated LncRNAs.mTOR Inhibition Rejuvenates the Aging Gingival Fibroblasts through Alleviating Oxidative Stress.Emerging roles of lncRNAs in senescence.Melanocytic nevi and melanoma: unraveling a complex relationship.Targeting the SASP to combat ageing: Mitochondria as possible intracellular allies?BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.To clear, or not to clear (senescent cells)? That is the question.Key proteins and pathways that regulate lifespan.Emerging links among Chromosome Instability (CIN), cancer, and aging.The Senescence-Associated Secretory Phenotype: Critical Effector in Skin Cancer and Aging.Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth.Impact of senescence-associated secretory phenotype and its potential as a therapeutic target for senescence-associated diseasesCell cycle RNA regulons coordinating early lymphocyte development.Senescence in Health and Disease.Demystifying the role of mitochondria in senescence.Virus/Host Cell Crosstalk in Hypoxic HPV-Positive Cancer Cells.Mitochondria and senescence: new actors for an old play.Induction of dormancy in hypoxic human papillomavirus-positive cancer cells.Controlling secretion to limit chemoresistance.Powering senescence: The ugly side of mitochondria.Cancer and Aging - the Inflammatory Connection.mTOR signaling orchestrates the expression of cytoprotective factors during cellular senescence.The Immortal Senescence.Unmasking Transcriptional Heterogeneity in Senescent Cells.TORn about SASP regulation.Targeted elimination of senescent Ras-transformed cells by suppression of MEK/ERK pathway.
P2860
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P2860
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@ast
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@en
type
label
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@ast
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@en
prefLabel
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@ast
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@en
P2093
P2860
P50
P356
P1433
P1476
mTOR regulates MAPKAPK2 transl ...... ssociated secretory phenotype.
@en
P2093
Alex Montoya
Andrew J Innes
Athena Georgilis
Florian Reisinger
Gareth J Thomas
Gopuraja Dharmalingam
Katharina Wolter
Lars Zender
Nicolás Herranz
P2860
P2888
P304
P356
10.1038/NCB3225
P50
P577
2015-08-17T00:00:00Z