about
4(1H)-pyridone and 4(1H)-quinolone derivatives as antimalarials with erythrocytic, exoerythrocytic, and transmission blocking activitiesMalaria: progress, perils, and prospects for eradicationOpen Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondGenetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic testsEffects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamineEffects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckeiA novel multiple-stage antimalarial agent that inhibits protein synthesis(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.Serial analysis of gene expression (SAGE) in Plasmodium falciparum: application of the technique to A-T rich genomes.Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta.Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activityOrigin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the PhilippinesRole of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.Novel arylimidamides for treatment of visceral leishmaniasis.Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South AmericaShagenes A and B, new tricyclic sesquiterpenes produced by an undescribed Antarctic octocoralRelationship between chloroquine toxicity and iron acquisition in Saccharomyces cerevisiae.The shikimate pathway and its branches in apicomplexan parasites.Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure.Quinolone-3-diarylethers: a new class of antimalarial drug.Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria.Antileishmanial activity of a series of N²,N⁴-disubstituted quinazoline-2,4-diaminesOrally bioavailable 6-chloro-7-methoxy-4(1H)-quinolones efficacious against multiple stages of Plasmodium.Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi.Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failurePhysical linkage to drug resistance genes results in conservation of var genes among West Pacific Plasmodium falciparum isolatesBis-benzimidazole hits against Naegleria fowleri discovered with new high-throughput screens.Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)Miniaturized Cultivation of Microbiota for Antimalarial Drug Discovery.Lead optimization of antimalarial propafenone analogues.Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds.Artemisinin-resistant Plasmodium falciparum parasites exhibit altered patterns of development in infected erythrocytesPhenotypic changes in artemisinin-resistant Plasmodium falciparum lines in vitro: evidence for decreased sensitivity to dormancy and growth inhibition.Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparumLead optimization of 3-carboxyl-4(1H)-quinolones to deliver orally bioavailable antimalarials.Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.Novel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitroCoibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins.Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery.
P50
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P50
description
onderzoeker
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researcher
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հետազոտող
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name
Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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type
label
Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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prefLabel
Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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Dennis E Kyle
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P106
P1153
7101627921
P21
P2381
P31
P496
0000-0002-0238-965X