about
Leupaxin negatively regulates B cell receptor signalingBasal immunoglobulin signaling actively maintains developmental stage in immature B cells.Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection.Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool.Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands.Bruton's tyrosine kinase and protein kinase C µ are required for TLR7/9-induced IKKα and IRF-1 activation and interferon-β production in conventional dendritic cellsThe ROQUIN family of proteins localizes to stress granules via the ROQ domain and binds target mRNAs.Macrophage polarization to a unique phenotype driven by B cells.Production of functional soluble Dectin-1 glycoprotein using an IRES-linked destabilized-dihydrofolate reductase expression vectorAnti-islet autoantibodies trigger autoimmune diabetes in the presence of an increased frequency of islet-reactive CD4 T cellsBruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral responseMajor histocompatibility complex class II expression distinguishes two distinct B cell developmental pathways during ontogeny.B cell antigen receptor specificity and surface density together determine B-1 versus B-2 cell development.Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells.Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells.Fas apoptosis inhibitory molecule is upregulated by IGF-1 signaling and modulates Akt activation and IRF4 expression in multiple myeloma.Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation.Fas apoptosis inhibitory molecule regulates T cell receptor-mediated apoptosis of thymocytes by modulating Akt activation and Nur77 expression.B-1 cells: unique origins and functions.Transmembrane activator, calcium modulator, and cyclophilin ligand interactor drives plasma cell differentiation in LPS-activated B cells.Delayed cellular maturation and decreased immunoglobulin kappa light chain production in immature B lymphocytes lacking B cell linker protein.DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.Proteomic analysis of the SH2 domain-containing leukocyte protein of 76 kDa (SLP76) interactome in resting and activated primary mast cells [corrected].The RNase III enzyme Dicer is essential for germinal center B-cell formation.Memory B-cell persistence is independent of persisting immunizing antigen.Genetic deletion of faim reveals its role in modulating c-FLIP expression during CD95-mediated apoptosis of lymphocytes and hepatocytes.Functional hierarchy and relative contribution of the CD28/B7 and ICOS/B7-H2 costimulatory pathways to T cell-mediated delayed-type hypersensitivity.In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.Comprehensive analysis of CD4+ T cells in the decision between tolerance and immunity in vivo reveals a pivotal role for ICOS.B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.BAFF costimulation of Toll-like receptor-activatedB-1 cellsA Conformational Change in Cytochromecof Apoptotic and Necrotic Cells Is Detected by Monoclonal Antibody Binding and Mimicked by Association of the Native Antigen with Synthetic Phospholipid Vesicles†Peritoneal CD5+ B-1 cells have signaling properties similar to tolerant B cellsCombined deficiencies in Bruton tyrosine kinase and phospholipase Cgamma2 arrest B-cell development at a pre-BCR+ stageDok-3 plays a nonredundant role in negative regulation of B-cell activationRegulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cellsBruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B CellsStochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivoT helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3
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P50
description
researcher
@en
wetenschapper
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հետազոտող
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name
Kong-Peng Lam
@ast
Kong-Peng Lam
@en
Kong-Peng Lam
@es
Kong-Peng Lam
@nl
Kong-Peng Lam
@sl
type
label
Kong-Peng Lam
@ast
Kong-Peng Lam
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Kong-Peng Lam
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Kong-Peng Lam
@nl
Kong-Peng Lam
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prefLabel
Kong-Peng Lam
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Kong-Peng Lam
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Kong-Peng Lam
@es
Kong-Peng Lam
@nl
Kong-Peng Lam
@sl
P106
P1153
7403657328
P31
P496
0000-0002-1316-4333