about
Constitutive type I interferon modulates homeostatic balance through tonic signalingFunctional crosstalk between type I and II interferon through the regulated expression of STAT1.STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformationA Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and functionMitochondrial STAT3: Powering up a potent factor.Cre-dependent DNA recombination activates a STING-dependent innate immune responseIFNgamma signaling-does it mean JAK-STAT?The JAK/STAT pathway in obesity and diabetes.Mitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progenyMitochondrial STAT3 supports Ras-dependent oncogenic transformation.A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes.Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns.JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer.The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine.Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice.The Role of p202 in Regulating Hematopoietic Cell Proliferation and DifferentiationSTAT3: a multifaceted oncoproteinDeep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancerToll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Daniel J Gough
@ast
Daniel J Gough
@en
Daniel J Gough
@es
Daniel J Gough
@nl
Daniel J Gough
@sl
type
label
Daniel J Gough
@ast
Daniel J Gough
@en
Daniel J Gough
@es
Daniel J Gough
@nl
Daniel J Gough
@sl
prefLabel
Daniel J Gough
@ast
Daniel J Gough
@en
Daniel J Gough
@es
Daniel J Gough
@nl
Daniel J Gough
@sl
P106
P21
P31
P496
0000-0001-6479-1735