Proparathyroid Hormone Is Preferentially Cleaved to Parathyroid Hormone by the Prohormone Convertase Furin - Wikidata - awgldk - TriplyDB

Proparathyroid Hormone Is Preferentially Cleaved to Parathyroid Hormone by the Prohormone Convertase Furin

Proparathyroid Hormone Is Preferentially Cleaved to Parathyroid Hormone by the Prohormone Convertase Furin

http://www.wikidata.org/entity/Q55953364

about

Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions.Induction of integral membrane PAM expression in AtT-20 cells alters the storage and trafficking of POMC and PC1.Parathyroid Hormone-Related Protein, Its Regulation of Cartilage and Bone Development, and Role in Treating Bone Diseases.Human furin Cys198 imposes dihedral and positional restraints on His194 for optimal Ser386-proton transfer.The proprotein convertase furin in tumour progression.In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor.Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.The contribution of arginine residues within the P6-P1 region of alpha 1-antitrypsin to its reaction with furin.In vitro characterization of the novel proprotein convertase PC7.

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Proparathyroid Hormone Is Preferentially Cleaved to Parathyroid Hormone by the Prohormone Convertase Furin

http://www.wikidata.org/entity/Q55953364

description

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

im April 1995 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published in Journal of Biological Chemistry

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована у квітні 1995

@uk

name

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@en

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@nl

type

label

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@en

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@nl

prefLabel

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@en

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@nl

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JBC.270.16.9517

P1433

Journal of Biological Chemistry

P1476

Proparathyroid Hormone Is Pref ...... he Prohormone Convertase Furin

@en

P2093

Bernard F. Gibbs

http://www.w3.org/2001/XMLSchema#string

Claude Lazure

http://www.w3.org/2001/XMLSchema#string

Geoffrey N. Hendy

http://www.w3.org/2001/XMLSchema#string

Hugh P. J. Bennett

http://www.w3.org/2001/XMLSchema#string

Nabil G. Seidah

http://www.w3.org/2001/XMLSchema#string

Robert Day

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleotide sequence of cloned cDNAs encoding human preproparathyroid hormone

cDNA and gene structure for a human subtilisin-like protease with cleavage specificity for paired basic amino acid residues

Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15

Proteolytic processing of chromogranin A in purified insulin granules. Formation of a 20 kDa N-terminal fragment (betagranin) by the concerted action of a Ca2+-dependent endopeptidase and carboxypeptidase H (EC 3.4.17.10)

Electron microscopic immunocytochemical evidence for the involvement of the convertases PC1 and PC2 in the processing of proinsulin in pancreatic beta-cells

Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

The determination of protein, oligonucleotide and peptide molecular weights by ion-spray mass spectrometry.

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.

Mammalian subtilisins: the long-sought dibasic processing endoproteases.

P304

9517-9525

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scholarly article

P356

10.1074/JBC.270.16.9517

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P407

P433

16

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P478

270

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P577

1995-04-21T00:00:00Z

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P5875

270871874

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