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RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression.Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variantsRGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activityGenomic organization and the 5' flanking region of the gamma subunit of the human amiloride-sensitive epithelial sodium channelRegulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling.A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription.Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins. Role of the RGS domain in stress-induced trafficking of RGS proteins.Immunostaining: detection of signaling protein location in tissues, cells and subcellular compartments.Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity.RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis.Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.Regulator of G protein signaling 6 is a critical mediator of both reward-related behavioral and pathological responses to alcoholDefective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channelsA truncated form of RGS3 negatively regulates G protein-coupled receptor stimulation of adenylyl cyclase and phosphoinositide phospholipase C.RGS6 as a Novel Therapeutic Target in CNS Diseases and Cancer.Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation.Nuclear trafficking of regulator of G protein signaling proteins and their roles in the nucleus.Introduction: G Protein-coupled Receptors and RGS Proteins.Two for the Price of One: G Protein-Dependent and -Independent Functions of RGS6 In Vivo.Multiple affinity and guanine nucleotide sensitive forms of the calcitonin gene related peptide (CGRP) receptor.RGS6, a modulator of parasympathetic activation in heart.RGS Proteins in Heart: Brakes on the Vagus.Stimulation of glycogenolysis and vasoconstriction by adenosine and adenosine analogues in the perfused rat liver.G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin.Essentiality of Regulator of G Protein Signaling 6 and Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II in Notch Signaling and Cardiovascular Development.Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury.Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation in RGS6-deficient miceCharacterization and regulation of high affinity calcitonin gene-related peptide receptors in cultured neonatal rat cardiac myocytesPlatelet-activating factor increases inositol phosphate production and cytosolic free Ca2+ concentrations in cultured rat Kupffer cellsStimulation and homologous desensitization of calcitonin gene-related peptide receptors in cultured beating rat heart cellsProtein mixed-disulfides in cardiac cells. S-thiolation of soluble proteins in response to diamideCholinergic receptor induction and JNK activation in acute pancreatitisIn vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine productionBile-pancreatic juice exclusion promotes Akt/NF-kappaB activation and chemokine production in ligation-induced acute pancreatitisBile-pancreatic juice exclusion increases cholinergic M3 and CCK-A receptor expression and interleukin-6 production in ligation-induced acute pancreatitisPreface. RGS Protein Physiology and PathophysiologyRegulators of G protein signaling in cardiovascular function during pregnancy
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wetenschapper
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հետազոտող
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R Fisher
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R Fisher
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R Fisher
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Rory Fisher
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7403555912
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P496
0000-0003-3108-4836