about
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma developmentPLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomasFoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasismicroRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma.p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.Mig-6 controls EGFR trafficking and suppresses gliomagenesisDNA-binding and transactivation activities are essential for TAp63 protein degradation.Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.ZNF365 promotes stability of fragile sites and telomeres.Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancerPTEN is a major tumor suppressor in pancreatic ductal adenocarcinoma and regulates an NF-κB-cytokine networkMDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein.The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.The MDM2 RING finger is required for cell cycle-dependent regulation of its protein expression.Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.IGF-1 activates p21 to inhibit UV-induced cell death.Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Hongwu Zheng
@ast
Hongwu Zheng
@en
Hongwu Zheng
@es
Hongwu Zheng
@nl
type
label
Hongwu Zheng
@ast
Hongwu Zheng
@en
Hongwu Zheng
@es
Hongwu Zheng
@nl
prefLabel
Hongwu Zheng
@ast
Hongwu Zheng
@en
Hongwu Zheng
@es
Hongwu Zheng
@nl
P106
P1153
7403440766
P31
P496
0000-0002-5823-4913