p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
about
TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradationGlioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressorPassenger deletions generate therapeutic vulnerabilities in cancerPLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomasFoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasisExciting new advances in neuro-oncology: the avenue to a cure for malignant gliomaRecent advances in the molecular understanding of glioblastomaExpression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine modelRadioresistance of Brain TumorsGlioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and RadioresistanceThe cell biology of disease: Acute promyelocytic leukemia, arsenic, and PML bodiesDevelopmental origins of brain tumorsBrain tumor stem cells: Molecular characteristics and their impact on therapyThe potential origin of glioblastoma initiating cellsWill kinase inhibitors make it as glioblastoma drugs?Epigenetic setting and reprogramming for neural cell fate determination and differentiationdp53 Restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and cyclin EA drosophila model for EGFR-Ras and PI3K-dependent human gliomaGlioblastoma: a pathogenic crosstalk between tumor cells and pericytesContributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zoneAsymmetric cell division of stem and progenitor cells during homeostasis and cancerThe C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivoThe level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesismir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult heartsThe adaptive significance of adult neurogenesis: an integrative approachOvercoming therapeutic resistance in glioblastoma: the way forwardTransformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation processA nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.The role of microRNAs in glioma initiation and progression.The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche.Thermally targeted delivery of a c-Myc inhibitory polypeptide inhibits tumor progression and extends survival in a rat glioma modelmicroRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma.Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastomaIdentification of mutated core cancer modules by integrating somatic mutation, copy number variation, and gene expression data.Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastomaRapamycin induces differentiation of glioma stem/progenitor cells by activating autophagyGlioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype.
P2860
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P2860
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@ast
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@en
type
label
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@ast
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@en
prefLabel
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@ast
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@en
P2093
P2860
P50
P356
P1433
P1476
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
@en
P2093
Alec C Kimmelman
An-Jou Chen
David J Hiller
Gerald C Chu
Giovanni Tonon
Haiyan Yan
Haoqiang Ying
Jayne M Stommel
Katherine L Dunn
Keith L Ligon
P2860
P2888
P304
P356
10.1038/NATURE07443
P407
P577
2008-10-01T00:00:00Z
P5875
P6179
1012998751