about
Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.Structural and dynamics characterization of norovirus proteaseOxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL ProteaseStructure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors.Characterization of group C rotaviruses associated with diarrhea outbreaks in feeder pigsSyntheses of 3-[(Alkylamino)methylene]-6-methylpyridine-2,4(1H,3H)-diones, 3-Substituted 7-Methyl-2H-pyrano[3,2-c]pyridine-2,5(6H)-dione Fluorescence Probes, and Tetrahydro-1H,9H-2,10-dioxa-9-azaanthracen-1-ones.Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay.Endosomal acidification and cathepsin L activity is required for calicivirus replication.The effects of simvastatin or interferon-α on infectivity of human norovirus using a gnotobiotic pig model for the study of antivirals.Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1.Biodegradable nanogels for oral delivery of interferon for norovirus infectionDesign, synthesis, and evaluation of inhibitors of Norwalk virus 3C protease.Broad-spectrum inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses.Magnitude of serum and intestinal antibody responses induced by sequential replicating and nonreplicating rotavirus vaccines in gnotobiotic pigs and correlation with protectionCyclosulfamide-based derivatives as inhibitors of norovirusesStructure-guided design and optimization of dipeptidyl inhibitors of norovirus 3CL protease. Structure-activity relationships and biochemical, X-ray crystallographic, cell-based, and in vivo studiesSynthesis and anti-norovirus activity of pyranobenzopyrone compounds.Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.Potent inhibition of enterovirus D68 and human rhinoviruses by dipeptidyl aldehydes and α-ketoamides.Potent inhibition of norovirus by dipeptidyl α-hydroxyphosphonate transition state mimics.Anti-norovirus therapeutics: a patent review (2010-2015).Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors.Recent Advances in the Discovery of Norovirus Therapeutics.Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.Inhibition of influenza virus replication by plant-derived isoquercetin.Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis.Design, Synthesis, and Evaluation of Novel Prodrugs of Transition State Inhibitors of Norovirus 3CL Protease.Design, synthesis, and evaluation of a novel series of macrocyclic inhibitors of norovirus 3CL protease.Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies.The crucial role of bile acids in the entry of porcine enteric calicivirusStructural and inhibitor studies of norovirus 3C-like proteases.Backbone and side-chain ¹H, ¹⁵N, and ¹³C resonance assignments of Norwalk virus protease.Novel triacsin C analogs as potential antivirals against rotavirus infections.Correction: Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor.Cell-culture propagation of porcine enteric calicivirus mediated by intestinal contents is dependent on the cyclic AMP signaling pathway.Trypsin-independent porcine epidemic diarrhea virus US strain with altered virus entry mechanism.Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.Comparisons of nucleotide and deduced amino acid sequences of NSP4 genes of virulent and attenuated pairs of group A and C rotaviruses.Fexaramine as an entry blocker for feline caliciviruses.
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Yunjeong Kim
@ast
Yunjeong Kim
@en
Yunjeong Kim
@es
Yunjeong Kim
@nl
type
label
Yunjeong Kim
@ast
Yunjeong Kim
@en
Yunjeong Kim
@es
Yunjeong Kim
@nl
prefLabel
Yunjeong Kim
@ast
Yunjeong Kim
@en
Yunjeong Kim
@es
Yunjeong Kim
@nl
P106
P31
P496
0000-0002-2977-4400