about
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposisRapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevityDepletion of Rictor, an essential protein component of mTORC2, decreases male lifespanThe LKB1 tumor suppressor kinase in human diseaseSuppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2.Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndromeStem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemnessTumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integritymTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.In vivo genome editing and organoid transplantation models of colorectal cancer and metastasisStromal Lkb1 deficiency leads to gastrointestinal tumorigenesis involving the IL-11-JAK/STAT3 pathway.A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.LKB1 in endothelial cells is required for angiogenesis and TGFbeta-mediated vascular smooth muscle cell recruitment.Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and AgingNotum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Pekka Katajisto
@ast
Pekka Katajisto
@en
Pekka Katajisto
@es
Pekka Katajisto
@nl
type
label
Pekka Katajisto
@ast
Pekka Katajisto
@en
Pekka Katajisto
@es
Pekka Katajisto
@nl
prefLabel
Pekka Katajisto
@ast
Pekka Katajisto
@en
Pekka Katajisto
@es
Pekka Katajisto
@nl
P106
P31
P496
0000-0002-3033-4189