about
Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responsesImmune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to PathogenicityTrypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B CellsInsufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout miceiNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant miceMouse models for pathogenic African trypanosomes: unravelling the immunology of host-parasite-vector interactions.Affinity is an important determinant of the anti-trypanosome activity of nanobodiesExperimental African Trypanosome Infection by Needle Passage or Natural Tsetse Fly Challenge Thwarts the Development of Collagen-Induced Arthritis in DBA/1 Prone Mice via an Impairment of Antigen Specific B Cell Autoantibody TitersSpecific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African TrypanosomiasisParallel selection of multiple anti-infectome Nanobodies without access to purified antigens.Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected miceMIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African TrypanosomosisHigh affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosisT. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosisIn situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice.Vaccination against trypanosomiasis: can it be done or is the trypanosome truly the ultimate immune destroyer and escape artist?Tsetse salivary gland proteins 1 and 2 are high affinity nucleic acid binding proteins with residual nuclease activity.Generation of a nanobody targeting the paraflagellar rod protein of trypanosomesDevelopment of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosisTsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.Detection of pathogen-specific antibodies by loop-mediated isothermal amplification.NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute AnemiaIL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ.An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase.Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei.African trypanosomosis: from immune escape and immunopathology to immune intervention.Contributions of experimental mouse models to the understanding of African trypanosomiasis.Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.African trypanosomiasis and antibodies: implications for vaccination, therapy and diagnosis.Current status of vaccination against African trypanosomiasis.Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake.A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron.African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?Comparative evaluation of the nested ITS PCR against the 18S PCR-RFLP in a survey of bovine trypanosomiasis in Kwale County, Kenya.Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment.The non-mammalian MIF superfamily.In vivo characterization of two additional Leishmania donovani strains using the murine and hamster model.
P50
Q21090522-3D1413C5-08FB-4718-B3BA-15A2CF0DEDC6Q26742172-5911EC91-10FC-4A1A-9F5E-C261D9D26CECQ27312822-8F77A481-00F6-4195-B2FB-E2CE77E54D14Q27313841-6878A417-592C-449C-85F9-C98BBC655CAEQ27316669-F213ED35-E337-47E5-9E60-AF48F420BAB6Q27686928-CCF4BE7C-21E6-45D0-99DB-3EDAE43988EEQ28485195-2B3DFCF2-6EE0-418F-994D-1D1165F005E0Q28545784-2AB47C5C-B475-4094-AAAB-B26215879133Q28545788-651148C4-4E61-4535-B3B1-3247FD5578BBQ30837722-3D733003-237F-4CAF-8F7B-91A12AA6B824Q31007389-4E774FFF-5E7A-4E3C-B64D-32C9E5C7C587Q33284533-05481DCC-BD81-4359-9F96-FB9152131F30Q33358673-E283690B-C645-46A8-9CA3-3F0A280CAE7DQ33435381-5CFA004D-9D4B-4B85-A49E-BAF71DDF1527Q33941028-7B845E97-B672-459D-803A-37CCFBEED064Q33954374-0EEB09AB-D8EA-46A2-8AA9-253B90AB1E63Q34220948-F326ADF1-CC2E-4518-90A9-D6C9B9D06F15Q34243439-36CA452A-7F8C-410A-AD7C-6407BFF069C8Q34460379-79069DD1-8312-4ADA-937C-09E9A6A8F700Q34796514-8BB8361A-9A01-412B-9AF2-6F97099065ADQ35157393-FD1A6E20-F98E-4840-A6E2-B713317462B0Q35217499-DD21ED75-E770-4959-9051-63101D6DC060Q35221201-7A321954-5E2C-4AB6-9A87-4953E1B3E1C6Q35662327-F96DA18A-6A10-4AF1-B6E8-153AB919E56FQ35722876-6C8DC15D-A14F-4D9F-AC0A-F66E8E8363C1Q35911914-4A8C4422-74C6-445D-BB66-C221F6F3F3C6Q36274117-9D992D8B-2453-46E2-934B-B2E43B6C898DQ36845492-AC3905AF-A4EC-427A-BCD0-E884DA0C64C0Q37236655-6C8C6B8B-EB65-41DA-BC03-8D642EFF676AQ37499204-2CF3273E-8201-4815-B0C1-77E3615E5D23Q37613678-F70CA26D-F909-470B-8A8B-F8F6E5F7313AQ37742202-DAEDEFFA-4416-42E2-8133-45B63EBD5CB0Q38283759-E1D78EA7-DF54-445E-BD14-071042AE9A34Q38299851-2D801536-196E-414C-8411-5D78890E80A0Q38532068-02A2355F-53E5-42FA-8C93-CE4C4300188EQ38735171-D9B337FB-802D-4849-A8FC-F6DCDD5FE83DQ38853789-5ECF3761-114E-43DE-B629-F5E4D079CFE7Q38879364-EC6B9AE3-B2A1-4820-AA6C-A2B9DF20B7DFQ38990641-873C22BB-07A0-451B-8179-64F1DC3C692EQ39124054-1A3E08F7-2F6C-4EB5-93B1-F84FE13B55F2
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Stefan Magez
@ast
Stefan Magez
@en
Stefan Magez
@es
Stefan Magez
@nl
type
label
Stefan Magez
@ast
Stefan Magez
@en
Stefan Magez
@es
Stefan Magez
@nl
prefLabel
Stefan Magez
@ast
Stefan Magez
@en
Stefan Magez
@es
Stefan Magez
@nl
P1053
D-9497-2014
P106
P21
P31
P3829
P496
0000-0003-3760-7968