A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

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Diacylglycerol kinase delta suppresses ER-to-Golgi traffic via its SAM and PH domains Oscillations in the lateral pressure of lipid monolayers induced by nonlinear chemical dynamics of the second messengers MARCKS and protein kinase C The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion Phosphoinositides: tiny lipids with giant impact on cell regulation The biphasic increase of PIP2 in the fertilized eggs of starfish: new roles in actin polymerization and Ca2+ signaling PIKfyve negatively regulates exocytosis in neurosecretory cells Plasma membrane phosphatidylinositol 4,5-bisphosphate levels decrease with time in culture In-cell protease assay systems based on trans-localizing molecular beacon proteins using HCV protease as a model system Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells CAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosis Clustering of syntaxin-1A in model membranes is modulated by phosphatidylinositol 4,5-bisphosphate and cholesterol.SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells.KCNQ5 channels control resting properties and release probability of a synapse Intersectin-1L nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc42 Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis.TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane.ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate Kinetic analysis of receptor-activated phosphoinositide turnover Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells.Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate.Neuronal calcium sensor-1 potentiates glucose-dependent exocytosis in pancreatic beta cells through activation of phosphatidylinositol 4-kinase beta.Annexin 2 promotes the formation of lipid microdomains required for calcium-regulated exocytosis of dense-core vesicles.Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion.Temporal and spatial coordination of exocytosis and endocytosis.ADP-ribosylation factor 6 regulates mammalian myoblast fusion through phospholipase D1 and phosphatidylinositol 4,5-bisphosphate signaling pathways.Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP.Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion.WASP is activated by phosphatidylinositol-4,5-bisphosphate to restrict synapse growth in a pathway parallel to bone morphogenetic protein signaling.Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs.PLCζ causes Ca(2+) oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P(2).PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells Motion matters: secretory granule motion adjacent to the plasma membrane and exocytosis Enteropathogenic Escherichia coli mediates antiphagocytosis through the inhibition of PI 3-kinase-dependent pathways.Role of synaptotagmin in Ca2+-triggered exocytosis.C2B polylysine motif of synaptotagmin facilitates a Ca2+-independent stage of synaptic vesicle priming in vivo.Polyphosphoinositide binding domains: Key to inositol lipid biology.Intracellular curvature-generating proteins in cell-to-cell fusion.Release of FGF1 and p40 synaptotagmin 1 correlates with their membrane destabilizing ability.Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion.Phosphoinositide and inositol phosphate analysis in lymphocyte activation

P2860

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P2860

A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in Exocytosis

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http://www.wikidata.org/entity/Q56689853

description

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

im März 2000 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published in Journal of Biological Chemistry

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в березні 2000

@uk