about
Discovery of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using virtual screening and scaffold hopping.Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.Effect of clinically approved HDAC inhibitors on Plasmodium, Leishmania and Schistosoma parasite growth.Identification of a sub-micromolar, non-peptide inhibitor of β-secretase with low neural cytotoxicity through in silico screening.Potent Small Agonists of Protease Activated Receptor 2.Molecular docking and structure-activity relationship studies on benzothiazole based non-peptidic BACE-1 inhibitors.Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand-modulated calcium signaling.Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets.Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signaling.Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2.Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery.Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Weijun Xu
@ast
Weijun Xu
@en
Weijun Xu
@es
Weijun Xu
@nl
type
label
Weijun Xu
@ast
Weijun Xu
@en
Weijun Xu
@es
Weijun Xu
@nl
prefLabel
Weijun Xu
@ast
Weijun Xu
@en
Weijun Xu
@es
Weijun Xu
@nl
P106
P1153
56510547300
P31
P496
0000-0002-3566-1082