Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis - Wikidata - awgldk - TriplyDB

Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis

Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis

http://www.wikidata.org/entity/Q56904639

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Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation On the predictive utility of animal models of osteoarthritis Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets The STR/ort mouse model of spontaneous osteoarthritis - an update Modifications of gait as predictors of natural osteoarthritis progression in STR/Ort mice Differentially expressed microRNAs in chondrocytes from distinct regions of developing human cartilage.Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis.Emerging targets in osteoarthritis therapy.Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition.Do mouse models reflect the diversity of osteoarthritis in humans?Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments.Endochondral Growth Defect and Deployment of Transient Chondrocyte Behaviors Underlie Osteoarthritis Onset in a Natural Murine Model Transcriptional profiling of cortical versus cancellous bone from mechanically-loaded murine tibiae reveals differential gene expression.Osteoarthritis: toward a comprehensive understanding of pathological mechanism.Mouse models of osteoarthritis: modelling risk factors and assessing outcomes.Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage.Models to define the stages of articular cartilage degradation in osteoarthritis development.Induced superficial chondrocyte death reduces catabolic cartilage damage in murine posttraumatic osteoarthritis.Stable sulforaphane protects against gait anomalies and modifies bone microarchitecture in the spontaneous STR/Ort model of osteoarthritis.Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures.Transcriptomics of wild-type mice and mice lacking ADAMTS-5 activity identifies genes involved in osteoarthritis initiation and cartilage destruction.Increased Activity of the Chondrocyte Translational Apparatus Accompanies Osteoarthritic Changes in Human and Rodent Knee Cartilage.Sexually dimorphic tibia shape is linked to natural osteoarthritis in STR/Ort mice.

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Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis

http://www.wikidata.org/entity/Q56904639

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scientific article published on 01 October 2012

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2012

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name

Time-series transcriptional pr ...... ility to murine osteoarthritis

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Time-series transcriptional pr ...... ility to murine osteoarthritis

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type

label

Time-series transcriptional pr ...... ility to murine osteoarthritis

@en

Time-series transcriptional pr ...... ility to murine osteoarthritis

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prefLabel

Time-series transcriptional pr ...... ility to murine osteoarthritis

@en

Time-series transcriptional pr ...... ility to murine osteoarthritis

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Arthritis and Rheumatism

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Time-series transcriptional pr ...... ility to murine osteoarthritis

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Andrew A Pitsillides

http://www.w3.org/2001/XMLSchema#string

Blandine Poulet

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Donald B Palmer

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Eleni Constantinou

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Matthew Pead

http://www.w3.org/2001/XMLSchema#string

Timothy C Stone

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Veronica Ulici

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Significance analysis of microarrays applied to the ionizing radiation response

Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans.

The STR/ort mouse and its use as a model of osteoarthritis.

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice.

Role of NF-kappaB transcription factors in antiinflammatory and proinflammatory actions of mechanical signals.

Animal models for arthritis.

Cartilage homeostasis in health and rheumatic diseases.

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism.

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3256-3266

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scholarly article

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10.1002/ART.34572

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10

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64

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James A Timmons

Valentina Gburcik

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2012-10-01T00:00:00Z

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22833266

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