about
Cortical Structure Alterations and Social Behavior Impairment in p50-Deficient MiceY682G Mutation of Amyloid Precursor Protein Promotes Endo-Lysosomal Dysfunction by Disrupting APP-SorLA Interaction.APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance.Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.Age-related changes of hippocampal synaptic plasticity in AβPP-null mice are restored by NGF through p75NTR.
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Luca R La Rosa
@ast
Luca R La Rosa
@en
Luca R La Rosa
@es
Luca R La Rosa
@nl
type
label
Luca R La Rosa
@ast
Luca R La Rosa
@en
Luca R La Rosa
@es
Luca R La Rosa
@nl
prefLabel
Luca R La Rosa
@ast
Luca R La Rosa
@en
Luca R La Rosa
@es
Luca R La Rosa
@nl
P106
P1153
53881394800
P31
P496
0000-0002-0367-9149