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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

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New and emerging disease modifying therapies for multiple sclerosis B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects B Cells in the Multiple Sclerosis Central Nervous System: Trafficking and Contribution to CNS-Compartmentalized Inflammation Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis Stage-Specific Role of Interferon-Gamma in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis Role of B cells in tolerance induction Epstein-Barr virus in systemic lupus erythematosus, rheumatoid arthritis and multiple sclerosis—association and causation Intrathecal IgG synthesis: a resistant and valuable target for future multiple sclerosis treatments Humoral-targeted immunotherapies in multiple sclerosis Myalgic encephalomyelitis/chronic fatigue syndrome and encephalomyelitis disseminata/multiple sclerosis show remarkable levels of similarity in phenomenology and neuroimmune characteristics Unraveling effector functions of B cells during infection: the hidden world beyond antibody production Restoring immune tolerance in neuromyelitis optica: Part II Neuroinflammation: Ways in Which the Immune System Affects the Brain Antigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases Comparative efficacy of alemtuzumab and established treatment in the management of multiple sclerosis Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action Therapeutic decisions in multiple sclerosis: moving beyond efficacy Circulating immune cells in multiple sclerosis.Therapeutic interference with leukocyte recirculation in multiple sclerosis.Progressive multiple sclerosis: from pathogenic mechanisms to treatment.Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells.Rituximab efficiently depletes increased CD20-expressing T cells in multiple sclerosis patients.IL-10 and lymphotoxin-α expression profiles within marginal zone-like B-cell populations are associated with control of HIV-1 disease progression.A novel microRNA-132-sirtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis [corrected].Rasmussen encephalitis and comorbid autoimmune diseases: A window into disease mechanism?The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs).Extensive grey matter pathology in the cerebellum in multiple sclerosis is linked to inflammation in the subarachnoid space.Systemic inflammation in progressive multiple sclerosis involves follicular T-helper, Th17- and activated B-cells and correlates with progression.Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity.Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein.Challenges in the pursuit of immune tolerance.The effect of glatiramer acetate therapy on functional properties of B cells from patients with relapsing-remitting multiple sclerosis.Is intrathecal anti-CD20 an option to target compartmentalized CNS inflammation in progressive MS?Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis Longitudinal analysis of T and B cell phenotype and function in renal transplant recipients with or without rituximab induction therapy.Update on the autoimmune pathology of multiple sclerosis: B-cells as disease-drivers and therapeutic targets Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders.B lymphocytes in neuromyelitis optica

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

http://www.wikidata.org/entity/Q57041523

description

article

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im April 2010 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована у квітні 2010

@uk

name

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

@en

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

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type

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

@en

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

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prefLabel

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

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Annals of Neurology

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

@en

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Aja Rieger

http://www.w3.org/2001/XMLSchema#string

Amit Bar-Or

http://www.w3.org/2001/XMLSchema#string

Boli Fan

http://www.w3.org/2001/XMLSchema#string

Christine Ghorayeb

http://www.w3.org/2001/XMLSchema#string

Craig H Smith

http://www.w3.org/2001/XMLSchema#string

Jiameng Zhang

http://www.w3.org/2001/XMLSchema#string

Lama Fawaz

http://www.w3.org/2001/XMLSchema#string

Peter J Darlington

http://www.w3.org/2001/XMLSchema#string

Stephen L Hauser

http://www.w3.org/2001/XMLSchema#string

P2860

Infectious causes of multiple sclerosis.

Mechanisms for the induction of autoimmunity by infectious agents.

Novel suppressive function of transitional 2 B cells in experimental arthritis.

Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis.

Autoreactive B cells discriminate CpG-rich and CpG-poor DNA and this response is modulated by IFN-alpha.

Human and murine CD4 T cell reactivity to a complex antigen: recognition of the synthetic random polypeptide glatiramer acetate.

Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

TLR-activated B cells suppress T cell-mediated autoimmunity.

CpG drives human transitional B cells to terminal differentiation and production of natural antibodies.

Distinct profiles of human B cell effector cytokines: a role in immune regulation?

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452-61

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scholarly article

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10.1002/ANA.21939

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P433

4

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67

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Emmanuelle Waubant

Peter A Calabresi

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2010-04-01T00:00:00Z

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P698

20437580

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