about
LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cellsEmerging functions of extracellular pyridine nucleotidesThe high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolismExtracellular NAD+ is an agonist of the human P2Y11 purinergic receptor in human granulocytesSynergistic interactions between HDAC and sirtuin inhibitors in human leukemia cellsG-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2Rejuvenating sirtuins: the rise of a new family of cancer drug targetsCatastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.Abscisic Acid: A Novel Nutraceutical for Glycemic Control.A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis.ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cellsBinding of abscisic acid to human LANCL2.The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts.Fluridone as a new anti-inflammatory drug.Discovery of novel and selective SIRT6 inhibitors.Selectivity hot-spots of sirtuin catalytic cores.Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messengerAbscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats.Autocrine and paracrine calcium signaling by the CD38/NAD+/cyclic ADP-ribose system.NAD+ levels control Ca2+ store replenishment and mitogen-induced increase of cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 channel gating in human T lymphocytes.The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responsesInhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarctionAntitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model.CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cellsNicotinamide phosphoribosyltransferase as a target in inflammation- related disorders.Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration.Autocrine abscisic acid plays a key role in quartz-induced macrophage activation.Autocrine abscisic acid mediates the UV-B-induced inflammatory response in human granulocytes and keratinocytes.Potent synergistic interaction between the Nampt inhibitor APO866 and the apoptosis activator TRAIL in human leukemia cells.Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-riboseNAADP+ is an agonist of the human P2Y11 purinergic receptor.Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated activation of murine N9 microglial cell line.Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation.Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.Spatio-temporal propagation of Ca2+ signals by cyclic ADP-ribose in 3T3 cells stimulated via purinergic P2Y receptors.The diadenosine homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-Tooth type 1A.P2X7-mediated increased intracellular calcium causes functional derangement in Schwann cells from rats with CMT1A neuropathy.Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo.Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Santina Bruzzone
@ast
Santina Bruzzone
@en
Santina Bruzzone
@es
Santina Bruzzone
@nl
type
label
Santina Bruzzone
@ast
Santina Bruzzone
@en
Santina Bruzzone
@es
Santina Bruzzone
@nl
prefLabel
Santina Bruzzone
@ast
Santina Bruzzone
@en
Santina Bruzzone
@es
Santina Bruzzone
@nl
P106
P21
P31
P496
0000-0003-2034-3716