about
G Protein-Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel ApproachesIdentification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.ETV5 cooperates with LPP as a sensor of extracellular signals and promotes EMT in endometrial carcinomas.New chromene scaffolds for adenosine A(2A) receptors: synthesis, pharmacology and structure-activity relationships.Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.Human breast cancer cell line MDA-MB-231 expresses endogenous A2B adenosine receptors mediating a Ca2+ signal.Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation.Distinct phosphorylation sites on the ghrelin receptor, GHSR1a, establish a code that determines the functions of ß-arrestins.Application of BRET for studying G protein-coupled receptors.Ligand Residence Time at G-protein-Coupled Receptors-Why We Should Take Our Time To Study It.The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.Phe369(7.38) at human 5-HT(7) receptors confers interspecies selectivity to antagonists and partial agonists.Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers.Development of Fluorescent Probes that Target Serotonin 5-HT2B Receptors.Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and beta-arrestins.Antibodies raised against the N-terminal sequence of delta opioid receptors blocked delta-mediated supraspinal antinociception in mice.Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to mu receptors.Serotonin 2A receptor disulfide bridge integrity is crucial for ligand binding to different signalling states but not for its homodimerization.In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic.QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine.Computer-aided structure-based design of multitarget leads for Alzheimer's disease.Novel insights on the structural determinants of clozapine and olanzapine multi-target binding profilesSynthesis of novel chromene scaffolds for adenosine receptorsNew Nitrogen Compounds Coupled to Phenolic Units with Antioxidant and Antifungal Activities: Synthesis and Structure⁻Activity RelationshipPhenolic Imidazole Derivatives with Dual Antioxidant/Antifungal Activity: Synthesis and Structure-Activity RelationshipSynthesis, Structural and Thermal Studies of 3-(1-Benzyl-1,2,3,6-tetrahydropyridin-4-yl)-5-ethoxy-1-indole (D2AAK1_3) as Dopamine D₂ Receptor LigandExtensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician populationOn a possible neutral charge state for the catalytic dyad in β-secretase when bound to hydroxyethylene transition state analogue inhibitorsCorrigendum to "In vitro, molecular modeling and behavioral studies of '3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic" [Neurochem. Int. 96 (2016) 84-99]N-(2-Hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1H- benzimidazol-1-yl)propyl]piperidine-4-Carboxamide (D2AAK4), a Multi-Target Ligand of Aminergic GPCRs, as a Potential Antipsychotic2-Aryladenine derivatives as a potent scaffold for A1, A3 and dual A1/A3 adenosine receptor antagonists: Synthesis and structure-activity relationshipsSynthesis, pharmacological and structural studies of 5-substituted-3-(1-arylmethyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as multi-target ligands of aminergic GPCRs1-(2'-Bromobenzyl)-6,7-dihydroxy-N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors
P50
Q28087277-28160424-225B-4182-9E9C-A00F111BCF67Q30990011-A493488B-74F3-4A16-B17F-3950FE04CF81Q34115829-A174E624-2B9D-4E12-B6E1-B8D3A1642385Q34248837-D546D04A-60CA-4EE7-A990-CEDF02AA6E63Q34296457-C7591D50-522A-4326-9442-D879E1E18DB6Q34544553-2742C1EF-B108-4908-8DE0-7B0D17B09120Q35048860-37276001-910F-4ABC-9403-C2F791E240D5Q35930273-ED2EF309-280F-4667-BF95-4D15CC417720Q36645363-C85586E9-6717-4415-8D59-E73C87C27695Q38207121-1E1A7CF4-0784-4DDF-81C5-EC6FFC85572AQ38543639-15BDECD4-70C5-4410-9146-27A1B1962023Q38928549-ACCB428B-BB6E-4EE5-8822-E465949A596DQ39640436-3273BCD6-95E5-4795-8CE9-EA97BBDF06CEQ39874127-73FACA7D-9829-4475-8A41-0FCA9EFF474EQ41538383-BC34E51A-67F1-40FC-B1ED-84C4C14423EEQ44142742-FBB2E674-70AC-44A0-B6CA-DF2ED0465368Q44338207-F24F7B5F-6637-4D73-AB93-EFD2F2E281E5Q44350218-55C292E0-3B19-4B44-81F6-110EAF1595F5Q47815362-F54E4437-ED98-4764-9DC0-40B9B274A1A3Q51738757-14771D49-772F-461C-B417-A29A52EEB4E9Q51807734-067E3653-A9F0-438A-AADE-5B58439A482EQ53359578-5124B42B-1B2C-47BC-BDEC-EEFEFA034D7BQ56979242-4B529899-EB0B-4DD1-BBEB-8CB1D9235DB0Q56992641-C1575DDD-B936-4597-9BFF-5297619C2929Q57039726-17228FB2-AA65-425A-920A-FC6C0EB00F4BQ57185233-4E09172B-EC50-4D0A-B958-6F55E87A17D8Q58696209-96BEA177-92D7-46A1-BCD6-3E4637D4559FQ79381706-1E388E62-55C5-43AD-98EB-2212DEF6DB16Q83754865-0150499D-9E38-47CA-8F1F-202C25A8B88FQ88720030-A4CE7AED-5DCA-4785-9E56-617D459CF5D3Q89896535-0F6A5066-EB46-41DE-A5AF-230B40D44B93Q91685587-E432DAD5-71FA-49B9-9E21-B8E67F474B9EQ92255203-79D05164-5FC6-4CF3-815B-76AEA1F62ADBQ92614821-E3529659-E2A8-47AF-A960-CBD4AC596D11
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Marian Castro
@ast
Marian Castro
@en
Marian Castro
@es
Marian Castro
@nl
type
label
Marian Castro
@ast
Marian Castro
@en
Marian Castro
@es
Marian Castro
@nl
altLabel
Marián Castro
@en
prefLabel
Marian Castro
@ast
Marian Castro
@en
Marian Castro
@es
Marian Castro
@nl
P1053
K-5747-2014
P106
P1153
13402994300
57186123900
P21
P2798
P31
P496
0000-0002-4732-1966