Phe369(7.38) at human 5-HT(7) receptors confers interspecies selectivity to antagonists and partial agonists.
about
Characterization of the dynamic events of GPCRs by automated computational simulations.Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.The arylpiperazine derivatives N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide and N-benzyl-4-(2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling.Synthesis and structure evaluation of new complex butylarylpiperazin-1-yl derivatives.Improvising 5-HT7R homology model for design of high affinity ligands: model validation with docking, embrace minimization, MM-GBSA, and molecular dynamic simulations.
P2860
Phe369(7.38) at human 5-HT(7) receptors confers interspecies selectivity to antagonists and partial agonists.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Phe369
@nl
Phe369(7.38) at human 5-HT(7) ...... agonists and partial agonists.
@en
type
label
Phe369
@nl
Phe369(7.38) at human 5-HT(7) ...... agonists and partial agonists.
@en
prefLabel
Phe369
@nl
Phe369(7.38) at human 5-HT(7) ...... agonists and partial agonists.
@en
P2093
P2860
P50
P1476
Phe369(7.38) at human 5-HT(7) ...... tagonists and partial agonists
@en
P2093
François Dauphin
Frederic Fabis
Javier Burgueño
Johan Aqvist
Jordi Rodrigo
Maria Isabel Loza
Pilar Perez
Thibault Varin
P2860
P304
P356
10.1111/J.1476-5381.2009.00481.X
P407
P577
2009-11-18T00:00:00Z