Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression - Wikidata - awgldk - TriplyDB

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

http://www.wikidata.org/entity/Q57142667

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The regulation of TGF-β/SMAD signaling by protein deubiquitination.A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor β-initiated prostate cancer epithelial-mesenchymal transition Prediagnostic circulating anti-Müllerian hormone concentrations are not associated with prostate cancer risk Risk for ESRD in type 1 diabetes remains high despite renoprotection.The PCa Tumor Microenvironment.The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of integrin-β8 in prostate cancer cells.Ad5/48 hexon oncolytic virus expressing sTGFβRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.Network analysis of an in vitro model of androgen-resistance in prostate cancer.Systemic delivery of oncolytic adenoviruses targeting transforming growth factor-β inhibits established bone metastasis in a prostate cancer mouse model.APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.Androgen regulation of epithelial-mesenchymal transition in prostate tumorigenesis The Endocrine Society Centennial: Hormones and Apoptosis in the Prostate Gland… Live and Let Die TGF-β1 regulates the invasive and metastatic potential of mucoepidermoid carcinoma cells Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches.Soy isoflavones and prostate cancer: a review of molecular mechanisms.TGF-beta signalling and immunity in prostate tumourigenesis.A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands.The reactive stroma microenvironment and prostate cancer progression.Autophagy in prostate cancer and androgen suppression therapy.Bone microenvironment-targeted manipulations for the treatment of osteoblastic metastasis in castration-resistant prostate cancer.Expression of TGFβ3 and its effects on migratory and invasive behavior of prostate cancer cells: involvement of PI3-kinase/AKT signaling pathway.Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage.Altered TGF-β signaling in a subpopulation of human stromal cells promotes prostatic carcinogenesis.Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation.A new therapy paradigm for prostate cancer founded on clinical observations.CCT6A suppresses SMAD2 and promotes prometastatic TGF-β signaling.The tumor microenvironment in prostate cancer: elucidating molecular pathways for therapy development MED15 overexpression in prostate cancer arises during androgen deprivation therapy via PI3K/mTOR signaling.NUSAP1 promotes invasion and metastasis of prostate cancer TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts.Increased CD8+ T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells.Reversion of epithelial-mesenchymal transition by a novel agent DZ-50 via IGF binding protein-3 in prostate cancer cells.Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells.Augmented anti-tumor activity of NK-92 cells expressing chimeric receptors of TGF-βR II and NKG2D.Profiling Prostate Cancer Therapeutic Resistance.Mechanisms navigating the TGF-β pathway in prostate cancer.Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a Smad2/3- and Src-dependent mechanism.Fatty Acids and Calcium Regulation in Prostate Cancer.Correlation between DEC1/DEC2 and epithelial‑mesenchymal transition in human prostate cancer PC‑3 cells

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Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

http://www.wikidata.org/entity/Q57142667

description

im Februar 2009 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в лютому 2009

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name

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

@en

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

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type

label

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

@en

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

@nl

prefLabel

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

@en

Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

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14728220802705696

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Expert Opinion on Therapeutic Targets

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Targeting TGF-beta in prostate cancer: therapeutic possibilities during tumor progression

@en

P2093

Elisabeth Jones

http://www.w3.org/2001/XMLSchema#string

Hong Pu

http://www.w3.org/2001/XMLSchema#string

Natasha Kyprianou

http://www.w3.org/2001/XMLSchema#string

P2860

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

New highlights on stroma-epithelial interactions in breast cancer.

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice

TGF-beta signaling in tumor suppression and cancer progression

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

Apoptosis in prostate carcinogenesis. A growth regulator and a therapeutic target.

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227-34

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scholarly article

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10.1517/14728220802705696

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2

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13

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2009-02-01T00:00:00Z

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19236240

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