Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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im September 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

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Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

@nl

P1476

Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms

@en

P2093

Sofia Giorgetti

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Creative Commons Attribution

P2860

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β

Hereditary systemic amyloidosis due to Asp76Asn variant β2-microglobulin

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

Sequestration of a β-hairpin for control of α-synuclein aggregation

Alpha-synuclein in Lewy bodies

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

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2677

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scholarly article

review article

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10.3390/IJMS19092677

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P407

English

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P478

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Paolo Tortora

Claudio Greco

Francesco Antonio Aprile

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2018-09-09T00:00:00Z

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30205618

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molecular biology

macromolecular substances

catalysis

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6164555

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