about
A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathologyC9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteinsEnhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease.Specific biomarkers for C9orf72 FTD/ALS could expedite the journey towards effective therapiesGenetic models of C9orf72: what is toxic?G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD.C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A
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Q24316080-C1D60960-C136-4C6C-9598-72F84176ED59Q37094833-85A7C498-EF92-4FF3-9F8F-25F3B0E777DFQ37706391-3463BFD8-5331-4353-A0FB-EEEE61A42771Q38557594-96381292-44B6-47D6-8286-B7AAE276AF40Q39212517-777085E2-2EE8-4167-A7C2-8C34AE8BCFDDQ47428803-FD679936-0EF1-4E23-9F74-1663E9E17069Q48145508-A78CA594-676E-4C3D-895B-DCD8A747CDD9Q63859498-50B61F43-E071-4B60-8C7D-26D52937CF47
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Thomas G Moens
@ast
Thomas G Moens
@en
Thomas G Moens
@es
Thomas G Moens
@nl
type
label
Thomas G Moens
@ast
Thomas G Moens
@en
Thomas G Moens
@es
Thomas G Moens
@nl
prefLabel
Thomas G Moens
@ast
Thomas G Moens
@en
Thomas G Moens
@es
Thomas G Moens
@nl
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P31
P496
0000-0002-4783-6257