A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology
about
The amyloid hypothesis of Alzheimer's disease at 25 yearsGene expression parallels synaptic excitability and plasticity changes in Alzheimer's diseaseLymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector.sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression.The Challenge of Stability in High-Throughput Gene Expression Analysis: Comprehensive Selection and Evaluation of Reference Genes for BALB/c Mice Spleen Samples in the Leishmania infantum Infection Model.Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease.The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer's diseaseBeneficial effects of increased lysozyme levels in Alzheimer's disease modelled in Drosophila melanogaster.TREM2 in Neurodegenerative Diseases.Polygenic risk score analysis of pathologically confirmed Alzheimer disease.Amylin Treatment Reduces Neuroinflammation and Ameliorates Abnormal Patterns of Gene Expression in the Cerebral Cortex of an Alzheimer's Disease Mouse Model.Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(Δexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology.Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging.Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer's Disease.TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy.Microglial repopulation resolves inflammation and promotes brain recovery after injury.The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation.Human Induced Pluripotent Stem Cells and the Modelling of Alzheimer's Disease: The Human Brain Outside the Dish.Triggering Receptor Expressed on Myeloid Cells 2 Overexpression Inhibits Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Microglia.Phagocytic Roles of Glial Cells in Healthy and Diseased Brains.Neuroinflammatory responses in Alzheimer's disease.Alzheimer's disease: where next for anti-amyloid therapies?Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure.Neuroprotective Effect of TREM-2 in Aging and Alzheimer's Disease Model.Clusterin levels are increased in Alzheimer's disease and influence the regional distribution of Aβ.Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.CXCR4 involvement in neurodegenerative diseases.Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration.PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activityHuman Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in PhagocytosisLoss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
P2860
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P2860
A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@ast
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en-gb
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@nl
type
label
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@ast
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en-gb
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@nl
prefLabel
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@ast
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en-gb
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@nl
P2093
P50
P921
P3181
P1433
P1476
A genome-wide gene-expression ...... nt of amyloid or tau pathology
@en
P2093
Dervis A Salih
Frances A Edwards
Jill C Richardson
John Hardy
Judy Latcham
Mar Matarin
Marina Perona
Marina Yasvoina
Michael Fulleylove
Rocio Moreno Paublete
P304
P3181
P356
10.1016/J.CELREP.2014.12.041
P407
P577
2015-01-22T00:00:00Z