Dual-function triazole-pyridine derivatives as inhibitors of metal-induced amyloid-β aggregation
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Synthetic Flavonoids, Aminoisoflavones: Interaction and Reactivity with Metal-Free and Metal-Associated Amyloid-β SpeciesSide-chain dynamics reveals transient association of Aβ(1-40) monomers with amyloid fibers.Reactivity of diphenylpropynone derivatives toward metal-associated amyloid-β species.Zn(II) ions substantially perturb Cu(II) ion coordination in amyloid-β at physiological pH.Metal complexes designed to bind to amyloid-β for the diagnosis and treatment of Alzheimer's disease.Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products.Ultraviolet light triggers the conversion of Cu2+-bound Aβ42 aggregates into cytotoxic species in a copper chelation-independent manner.Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models.3-Hydroxy-4-pyridinone derivatives as metal ion and amyloid binding agents.Synthesis, characterization, and biological studies of emissive rhenium-glutamine conjugates.Multi-target-directed phenol-triazole ligands as therapeutic agents for Alzheimer's disease.Tricarbonylrhenium complexes from 2-pyridyl-1,2,3-triazole ligands bearing a 4-substituted phenyl arm: a combined experimental and theoretical study.The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof.Crystal structure of catena-poly[[[di-chlorido-copper(II)]-{μ-tert-butyl N-methyl-N-[4-(6-{[4-(pyridin-2-yl-κN)-1H-1,2,3-triazol-1-yl-κN3]meth-yl}-1,3-benzo-thia-zol-2-yl)phen-yl]carbamato}] aceto-nitrile monosolvate].
P2860
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P2860
Dual-function triazole-pyridine derivatives as inhibitors of metal-induced amyloid-β aggregation
description
article
@en
im August 2012 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2012
@uk
name
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@en
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@nl
type
label
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@en
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@nl
altLabel
Dual-function triazole–pyridin ...... -induced amyloid-β aggregation
@en
Dual-function triazole–pyridin ...... -induced amyloid-β aggregation
@nl
prefLabel
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@en
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@nl
P2093
P2860
P356
P1433
P1476
Dual-function triazole-pyridin ...... -induced amyloid-β aggregation
@en
P2093
Alaina S DeToma
Erin L Service
Isaac J Kimsey
John R Thompson
Mi Hee Lim
Michael C P Wang
Michael R Jones
P2860
P304
P356
10.1039/C2MT20113E
P407
P577
2012-08-01T00:00:00Z