T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes
about
Lck domains differentially contribute to pre-T cell receptor (TCR)- and TCR-alpha/beta-regulated developmental transitionsThe CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta lociRequirement of CD3 complex-associated signaling functions for expression of rearranged T cell receptor beta VDJ genes in early thymic developmentRegulation of T cell receptor (TCR) beta gene expression by CD3 complex signaling in immature thymocytes: implications for TCRbeta allelic exclusionTEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.A transgenic mouse model of human T cell leukemia virus type 1-associated diseases.The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function.Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity.Chimeric protein of CD8a extracellular domain and CD4 transmembrane and cytoplasmic domain binds more efficiently to p56lck than CD8a
P2860
Q36375946-12324836-5A0A-4B88-A117-844D296721ACQ36381026-677A8786-48C9-4B1F-B993-E7DA82348EE6Q36401626-F2756177-FDC5-4EB1-B2B8-3790E698EBDDQ36454147-F7E06E1D-822A-4B48-BD76-B9652A50A305Q37219806-E0C82252-9006-4E2E-A174-F16F8E5BCB96Q41438051-49CAA373-9574-4A2E-A505-D8BEEB538727Q41708197-F7C04979-4DBB-4C88-B83F-1F780C96A6BBQ41899175-7007DA98-2FD6-4723-9E69-9668AB8E6657Q43513983-43EA44E4-F159-4542-9117-61727301F332Q58134165-271A1F8D-5F55-4B95-AD22-7CA39793C22F
P2860
T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes
description
article
@en
im Mai 1995 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 1995
@uk
name
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@en
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@nl
type
label
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@en
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@nl
prefLabel
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@en
T lymphocyte development in p5 ...... by TcR β or TcR αβ transgenes
@nl
P2093
P50
P356
P1476
T lymphocyte development in p5 ...... a or TcR alpha beta transgenes
@en
P2093
Eichmann K
Kishihara K
Wallace VA
P304
P356
10.1002/EJI.1830250527
P407
P577
1995-05-01T00:00:00Z