Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
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Ecology and transmission of Buruli ulcer disease: a systematic reviewLarge sequence polymorphisms unveil the phylogenetic relationship of environmental and pathogenic mycobacteria related to Mycobacterium ulceransPhylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans diseaseThe pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ERMassive comparative genomic analysis reveals convergent evolution of specialized bacteriaInterplay of heritage and habitat in the distribution of bacterial signal transduction systemsMycolactone impairs T cell homing by suppressing microRNA control of L-selectin expressionGenotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.Estimation of Gene Insertion/Deletion Rates with Missing DataPhylogenetic detection of horizontal gene transfer during the step-wise genesis of Mycobacterium tuberculosisContrasting persistence strategies in Salmonella and MycobacteriumScalable and efficient synthesis of the mycolactone core.Heterogeneous Family of Cyclomodulins: Smart Weapons That Allow Bacteria to Hijack the Eukaryotic Cell Cycle and Promote Infections.Rhomboid homologs in mycobacteria: insights from phylogeny and genomic analysis.Synthesis and structure assignment of the minor metabolite arising from the frog pathogen Mycobacterium liflandii.Global and local environmental changes as drivers of Buruli ulcer emergenceA severe case of Buruli ulcer disease with pleural effusionsMycolactone diffuses into the peripheral blood of Buruli ulcer patients--implications for diagnosis and disease monitoring.Growth, cell division and sporulation in mycobacteria.Risk of Buruli ulcer and detection of Mycobacterium ulcerans in mosquitoes in southeastern Australia.Spontaneous clearance of Mycobacterium ulcerans in a case of Buruli ulcerMacrophage cytokines: involvement in immunity and infectious diseasesOn the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer.Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis.Primary cultivation: factors affecting contamination and Mycobacterium ulcerans growth after long turnover time of clinical specimens.Chemistry of mycolactones, the causative toxins of Buruli ulcer.Comparative phylogenomics of pathogenic and non-pathogenic mycobacterium.Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer diseaseInsight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosisTreating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife?Shaping mycolactone for therapeutic use against inflammatory disorders.Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice.Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulceransMycobacterium ulcerans Mouse Model Refinement for Pre-Clinical Profiling of Vaccine Candidates.Multiple Introductions and Recent Spread of the Emerging Human Pathogen Mycobacterium ulcerans across AfricaMetabolomic profiles delineate mycolactone signature in Buruli ulcer disease.Local Heat Application for the Treatment of Buruli Ulcer: Results of a Phase II Open Label Single Center Non Comparative Clinical Trial.Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.Highly stereoselective total synthesis of fully hydroxy-protected mycolactones A and B and their stereoisomerization upon deprotection
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Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
description
article
@en
im Januar 2009 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2009
@uk
name
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@en
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@nl
type
label
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@en
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@nl
prefLabel
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@en
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@nl
P2093
P2860
P356
P1476
Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans
@en
P2093
Caroline Demangel
Stewart T. Cole
Timothy P. Stinear
P2860
P2888
P356
10.1038/NRMICRO2077
P407
P577
2009-01-01T00:00:00Z