Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a - Wikidata - awgldk - TriplyDB

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

http://www.wikidata.org/entity/Q57277034

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Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling Tumor suppressors: enhancers or suppressors of regeneration?mTOR: from growth signal integration to cancer, diabetes and ageing Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging Susceptibility loci for intracranial aneurysm in European and Japanese populations Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging Immunosenescence: emerging challenges for an ageing population Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells Two faces of p53: aging and tumor suppression Molecular dissection of formation of senescence-associated heterochromatin foci Rapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its function Aging of hematopoietic stem cells: DNA damage and mutations?DNA Damage Response in Hematopoietic Stem Cell Ageing Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function When stem cells grow old: phenotypes and mechanisms of stem cell aging Strategies to Enhance the Effectiveness of Adult Stem Cell Therapy for Ischemic Heart Diseases Affecting the Elderly Patients Critical Roles of Reactive Oxygen Species in Age-Related Impairment in Ischemia-Induced Neovascularization by Regulating Stem and Progenitor Cell Function Changes in Regenerative Capacity through Lifespan Adiponectin as a potential biomarker of vascular disease Genetic regulation of thymocyte progenitor aging Immunosenescence and organ transplantation Hematopoietic stem cell niche maintenance during homeostasis and regeneration Potential of cardiac stem/progenitor cells and induced pluripotent stem cells for cardiac repair in ischaemic heart disease Roles of FGF signaling in stem cell self-renewal, senescence and aging Therapeutic targeting of replicative immortality Reproductive Aging Drives Protein Accumulation in the Uterus and Limits Lifespan in C. elegans Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion Adult stem cell and mesenchymal progenitor theories of aging.Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18 The hallmarks of aging Immortalization eliminates a roadblock during cellular reprogramming into iPS cells Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss The epigenomics of cancer Impact of genomic damage and ageing on stem cell function Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Defining the toxicology of aging The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche

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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

http://www.wikidata.org/entity/Q57277034

description

article publié dans la revue scientifique Nature

@fr

scientific article published in Nature

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature у вересні 2006

@uk

name

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@en

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@nl

type

label

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@en

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@nl

prefLabel

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@en

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

@nl

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Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

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David M Dombkowski

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David T Scadden

http://www.w3.org/2001/XMLSchema#string

Heather E Fleming

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Michael T Waring

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Randolf Forkert

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Ronald A DePinho

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Tao Cheng

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Viktor Janzen

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Yoriko Saito

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421-426

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scholarly article

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10.1038/NATURE05159

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7110

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443

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Norman Sharpless

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2006-09-06T00:00:00Z

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1033229938

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