Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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Emerging role of precision medicine in biliary tract cancers

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P1476

Emerging role of precision medicine in biliary tract cancers

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P2093

Daniel H Ahn

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James M Bogenberger

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Mansi Arora

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Mitesh J Borad

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Thomas T DeLeon

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P2860

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression

A microRNA expression signature of human solid tumors defines cancer gene targets

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation

Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase

Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma

Histone demethylation by a family of JmjC domain-containing proteins.

P2888

s41698-018-0064-z

P304

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P31

scholarly article

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10.1038/S41698-018-0064-Z

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P407

English

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P478

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P577

2018-01-01T00:00:00Z

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P698

30302397

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P932

6170410

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