about
AID-induced remodeling of immunoglobulin genes and B cell fate.Premature replacement of mu with alpha immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation.Immunologic basis for the rare occurrence of true nonsecretory plasma cell dyscrasias.The pathogenesis and diagnosis of acute kidney injury in multiple myeloma.Al amyloidosisA plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig productionImpaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi SyndromeToward understanding renal Fanconi syndrome: step by step advances through experimental models.Cross talk between immunoglobulin heavy-chain transcription and RNA surveillance during B cell development.A mouse model recapitulating human monoclonal heavy chain deposition disease evidences the relevance of proteasome inhibitor therapy.Kidney diseases associated with monoclonal immunoglobulin M-secreting B-cell lymphoproliferative disorders: a case series of 35 patients.B-cell receptor signal strength influences terminal differentiation.Mesangial cells as amyloid factory: a unique contribution of animal models.Light chain deposition disease without glomerular proteinuria: a diagnostic challenge for the nephrologist.Efficient AID targeting of switch regions is not sufficient for optimal class switch recombination.Animal models of monoclonal immunoglobulin-related renal diseases.[Randall-type monoclonal immunoglobulin deposition disease: From diagnosis to treatment].Unravelling the immunopathological mechanisms of heavy chain deposition disease with implications for clinical management.[Classification and therapeutic management of monoclonal gammopathies of renal significance].Strategies to model AL amyloidosis in mice.Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B CellsComprehensive molecular characterization of a heavy chain deposition disease caseRandall-type monoclonal immunoglobulin deposition disease: novel insights from a nationwide cohort studyFanconi's syndrome induced by a monoclonal Vkappa3 light chain in Waldenstrom's macroglobulinemiaRole of the monoclonal kappa chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndrome[Renal disorders associated with monoclonal gammopathies: diagnostic and therapeutic progress]Production of human or humanized antibodies in micePhysiological and druggable skipping of immunoglobulin variable exons in plasma cells
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P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
研究者
@zh
name
Christophe Sirac
@ast
Christophe Sirac
@en
Christophe Sirac
@es
Christophe Sirac
@nl
type
label
Christophe Sirac
@ast
Christophe Sirac
@en
Christophe Sirac
@es
Christophe Sirac
@nl
prefLabel
Christophe Sirac
@ast
Christophe Sirac
@en
Christophe Sirac
@es
Christophe Sirac
@nl
P106
P1153
6506516563
P31
P496
0000-0002-1183-4989