about
Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cellsWSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteriaHuman dendritic cells activated by TSLP and CD40L induce proallergic cytotoxic T cellsIL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cellsInterleukin-10The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chainsGlucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestineInterleukin-19: a constituent of the regulome that controls antigen presenting cells in the lungs and airway responses to microbial productsDevelopment, cytokine profile and function of human interleukin 17-producing helper T cellsGITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cellsNod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice.IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18.T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis.Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS).Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis.IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesisFunctional characterization of human IL-10.Expression patterns of IL-10 ligand and receptor gene families provide leads for biological characterization.IL-12 and IL-23: master regulators of innate and adaptive immunity.Molecular regulation of Th2 immunity by dendritic cells.Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.Pulmonary arterial remodeling induced by a Th2 immune responseIL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunizationInterleukin-10 promotes Mycobacterium tuberculosis disease progression in CBA/J miceFrom interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited.Development and function of TH17 cells in health and disease.Glucocorticoid-Induced TNF Receptor Family-Related Protein Ligand is Requisite for Optimal Functioning of Regulatory CD4(+) T Cells.Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation.IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in miceInterleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.Effects of interleukin 4 on monocyte functions: comparison to interleukin 13.A clinical biomarker assay to quantitate thymic stromal lymphopoietin in human plasma at sub-pg/ml level.Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.
P50
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P50
description
researcher ORCID ID = 0000-0002-2663-383X
@en
wetenschapper
@nl
name
René de Waal Malefyt
@ast
René de Waal Malefyt
@en
René de Waal Malefyt
@es
René de Waal Malefyt
@nl
type
label
René de Waal Malefyt
@ast
René de Waal Malefyt
@en
René de Waal Malefyt
@es
René de Waal Malefyt
@nl
prefLabel
René de Waal Malefyt
@ast
René de Waal Malefyt
@en
René de Waal Malefyt
@es
René de Waal Malefyt
@nl
P106
P1153
7005006679
P31
P496
0000-0002-2663-383X