Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. - Wikidata - awgldk - TriplyDB

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.

http://www.wikidata.org/entity/Q41330684

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Differential expression of CD300a/c on human TH1 and TH17 cells Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases Circulating Th17, Th22, and Th1 cells are increased in psoriasis MCAM-expressing CD4(+) T cells in peripheral blood secrete IL-17A and are significantly elevated in inflammatory autoimmune diseases Beyond ecto-nucleotidase: CD39 defines human Th17 cells with CD161 Modulation of NK cell function by genetically coupled C-type lectin-like receptor/ligand pairs encoded in the human natural killer gene complex Th22 cells in allergic disease Regulation of T helper cell subsets by cyclooxygenases and their metabolites Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties T Cell Interstitial Migration: Motility Cues from the Inflamed Tissue for Micro- and Macro-Positioning Involvement of the IL-22/REG Ialpha axis in ulcerative colitis Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1)Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.A novel mechanism of soluble HLA-G mediated immune modulation: downregulation of T cell chemokine receptor expression and impairment of chemotaxis.IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis.Complexity and Diversity of the NKR-P1:Clr (Klrb1:Clec2) Recognition Systems The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans Monocytes differentiated with IL-15 support Th17 and Th1 responses to wheat gliadin: implications for celiac disease.Decidual stromal cells recruit Th17 cells into decidua to promote proliferation and invasion of human trophoblast cells by secreting IL-17 Tumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel disease Th17 cytokines in mucosal immunity and inflammation.Antagonizing arachidonic acid-derived eicosanoids reduces inflammatory Th17 and Th1 cell-mediated inflammation and colitis severity.Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis Th17-related cytokines: new players in the control of chronic intestinal inflammation Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment Crohn disease: a current perspective on genetics, autophagy and immunity CD39 and CD161 modulate Th17 responses in Crohn's disease.Heme oxygenase-1 ameliorates dextran sulfate sodium-induced acute murine colitis by regulating Th17/Treg cell balance.Host defense mechanisms in secondary syphilitic lesions: a role for IFN-gamma-/IL-17-producing CD8+ T cells?Human CCR4+ CCR6+ Th17 cells suppress autologous CD8+ T cell responses.Studying the human immunome: the complexity of comprehensive leukocyte immunophenotyping.Effector CD4+ T cell expression signatures and immune-mediated disease associated genes.Role of interleukin-22 in inflammatory bowel disease Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammation CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells Modeling of celiac disease immune response and the therapeutic effect of potential drugs IFN-γ and IL-17: the two faces of T-cell pathology in giant cell arteritis Th17 cells in cancer: help or hindrance?

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.

http://www.wikidata.org/entity/Q41330684

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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name

Circulating and gut-resident h ...... omote intestinal inflammation.

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type

label

Circulating and gut-resident h ...... omote intestinal inflammation.

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Circulating and gut-resident h ...... omote intestinal inflammation.

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Journal of Experimental Medicine

P1476

Circulating and gut-resident h ...... omote intestinal inflammation.

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P2093

Bela Desai

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Erin E Murphy

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Jeff Grein

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Lisa Raskin

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Melanie A Kleinschek

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Robert A Kastelein

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Robert H Pierce

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Scott P Turner

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Svetlana Sadekova

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Terrill McClanahan

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P2860

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes

The biological functions of T helper 17 cell effector cytokines in inflammation

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Development, cytokine profile and function of human interleukin 17-producing helper T cells

Phenotypic and functional features of human Th17 cells

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

CD4+,CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems.

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525-534

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10.1084/JEM.20081712

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P433

3

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206

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René de Waal Malefyt

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2009-03-09T00:00:00Z

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24188937

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19273624

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2699125

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