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The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cellsThe NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cellsEvaluation of genome-wide expression profiles of blood and sputum neutrophils in cystic fibrosis patients before and after antibiotic therapy.Correction of defective CFTR/ENaC function and tightness of cystic fibrosis airway epithelium by amniotic mesenchymal stromal (stem) cells.ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasionCFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity.The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.Local modulation of cystic fibrosis conductance regulator: cytoskeleton and compartmentalized cAMP signalling.Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR)Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model.A novel NHE1-centered signaling cassette drives epidermal growth factor receptor-dependent pancreatic tumor metastasis and is a target for combination therapy.Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1.NHE3 inhibits PKA-dependent functional expression of CFTR by NHERF2 PDZ interactions.Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells.Extracellular adenine nucleotides regulate Na+/H+ exchanger NHE3 activity in A6-NHE3 transfectants by a cAMP/PKA-dependent mechanism.Molecular aspects of acute inhibition of Na(+)-H(+) exchanger NHE3 by A(2)-adenosine receptor agonists.Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells.Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.Association of pS2 (TFF1) release with breast tumour proliferative rate: in vitro and in vivo studies.Adenosine inhibits the transfected Na+-H+ exchanger NHE3 in Xenopus laevis renal epithelial cells (A6/C1).Effect of cycloheximide on urea facilitated transport through toad gallbladder epithelium.Protective effect of hydrocortisone on vasopressin response in frog skin.Increase in interleukin-8 production from circulating neutrophils upon antibiotic therapy in cystic fibrosis patients.Effects of beta-endorphin and Naloxone on in vitro maturation of bovine oocytes.Permeability pathways for non-electrolytes through Bufo bufo gall-bladder.Expression and localization of the mu-opioid receptor (MOR) in the equine cumulus-oocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence.The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation.Short- and long-term A3 adenosine receptor activation inhibits the Na+/H+ exchanger NHE3 activity and expression in opossum kidney cells.Antibiotic therapy affects functional behaviour in cystic fibrosis blood mononuclear cells.[Effect of ionophore A23187 on the response to ADH in the ventral skin of Rana esculenta]Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cellsNHE1 promotes invadopodial ECM proteolysis through acidification of the peri-invadopodial spacePhorbol ester effect on the hydrosmotic response to vasopressin in frog skin
P50
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P50
description
researcher ORCID ID = 0000-0003-4471-4948
@en
wetenschapper
@nl
name
Valeria Casavola
@ast
Valeria Casavola
@en
Valeria Casavola
@es
Valeria Casavola
@nl
type
label
Valeria Casavola
@ast
Valeria Casavola
@en
Valeria Casavola
@es
Valeria Casavola
@nl
prefLabel
Valeria Casavola
@ast
Valeria Casavola
@en
Valeria Casavola
@es
Valeria Casavola
@nl
P106
P31
P496
0000-0003-4471-4948