Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status
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Discovery and resupply of pharmacologically active plant-derived natural products: A reviewEllagitannins in Cancer Chemoprevention and TherapyUrolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells.Pomegranate extract induces ellagitannin metabolite formation and changes stool microbiota in healthy volunteers.Effect of daily intake of pomegranate juice on fecal microbiota and feces metabolites from healthy volunteers.Plasma metabolomic biomarkers of mixed nuts exposure inversely correlate with severity of metabolic syndrome.Gastrointestinal stability of urolithins: an in vitro approach.The human gut microbial ecology associated with overweight and obesity determines ellagic acid metabolism.The microbial pharmacists within us: a metagenomic view of xenobiotic metabolismPlasma and Urinary Phenolic Profiles after Acute and Repetitive Intake of Wild Blueberry.Health benefits of walnut polyphenols: An exploration beyond their lipid profile.Potential antiproliferative activity of polyphenol metabolites against human breast cancer cells and their urine excretion pattern in healthy subjects following acute intake of a polyphenol-rich juice of grumixama (Eugenia brasiliensis Lam.).Effect of urolithins on oxidative stress of colorectal adenocarcinomacells-Caco-2.Worldwide (poly)phenol intake: assessment methods and identified gaps.Understanding the Molecular Mechanisms of the Interplay Between Herbal Medicines and Gut Microbiota.Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism.Urolithins, the rescue of "old" metabolites to understand a "new" concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status.Use of Polyphenolic Compounds in Dermatologic Oncology.The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells.Prebiotic nut compounds and human microbiota.The Chemistry of Gut Microbial Metabolism of Polyphenols.Improvements in Metabolic Health with Consumption of Ellagic Acid and Subsequent Conversion into Urolithins: Evidence and Mechanisms.Altered Transport and Metabolism of Phenolic Compounds in Obesity and Diabetes: Implications for Functional Food Development and Assessment.Gut microbiota functions: metabolism of nutrients and other food components.Interindividual Variability in Biomarkers of Cardiometabolic Health after Consumption of Major Plant-Food Bioactive Compounds and the Determinants Involved.Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD.Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid.Diverse Phytochemicals and Bioactivities in the Ancient Fruit and Modern Functional Food Pomegranate (Punica granatum).Benefits of Nut Consumption on Insulin Resistance and Cardiovascular Risk Factors: Multiple Potential Mechanisms of Actions.Quercetin and isorhamnetin aglycones are the main metabolites of dietary quercetin in cerebrospinal fluid.Metabolic fate of strawberry polyphenols after chronic intake in healthy older adults.Differentiated Caco-2 cell monolayers exhibit adaptation in the transport and metabolism of flavan-3-ols with chronic exposure to both isolated flavan-3-ols and enriched extracts.Impact of dietary gut microbial metabolites on the epigenome.Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses.MicroRNAs expression in normal and malignant colon tissues as biomarkers of colorectal cancer and in response to pomegranate extracts consumption: Critical issues to discern between modulatory effects and potential artefacts.Application of a low polyphenol or low ellagitannin dietary intervention and its impact on ellagitannin metabolism in men.Validation of biomarkers of food intake-critical assessment of candidate biomarkers.Urolithin A, C, and D, but not iso-urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes.Pomegranate ellagitannins inhibit α-glucosidase activityin vitroand reduce starch digestibility under simulated gastro-intestinal conditions
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Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status
description
article
@en
im Juli 2014 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 2014
@uk
name
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@en
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@nl
type
label
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@en
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@nl
prefLabel
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@en
Ellagic Acid Metabolism by Hum ...... Source, Age, and Health Status
@nl
P2093
P50
P356
P1476
Ellagic acid metabolism by hum ...... source, age, and health status
@en
P2093
Antonio González-Sarrías
Francisco A. Tomás-Barberán
Juan C. Espín
María V. Selma
Rocío García-Villalba
P304
P356
10.1021/JF5024615
P407
P50
P577
2014-07-01T00:00:00Z