Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma - Wikidata - awgldk - TriplyDB

Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma

Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma

http://www.wikidata.org/entity/Q57817523

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The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal function Pheochromocytomas and Paragangliomas: Clinical and Genetic Approaches Target therapy in metastatic pheochromocytoma: current perspectives and controversies Integrative analysis of neuroblastoma and pheochromocytoma genomics data.Rare germline mutations identified by targeted next-generation sequencing of susceptibility genes in pheochromocytoma and paraganglioma.Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma Anti-cancer potential of MAPK pathway inhibition in paragangliomas-effect of different statins on mouse pheochromocytoma cells.Molecular markers of paragangliomas/pheochromocytomas Mitochondrial Deficiencies in the Predisposition to Paraganglioma Current approaches and recent developments in the management of head and neck paragangliomas.Identity by descent mapping of founder mutations in cancer using high-resolution tumor SNP data.Pheochromocytoma and paraganglioma: diagnosis, genetics, management, and treatment The size of the primary tumor and age at initial diagnosis are independent predictors of the metastatic behavior and survival of patients with SDHB-related pheochromocytoma and paraganglioma: a retrospective cohort study Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.P.Arg82Leu von Hippel-Lindau (VHL) gene mutation among three members of a family with familial bilateral pheochromocytoma in India: molecular analysis and in silico characterization.Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas.Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas.Profiling of somatic mutations in phaeochromocytoma and paraganglioma by targeted next generation sequencing analysis.Role of miR-101 in pheochromocytoma patients with SDHD mutation.Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism.Pheochromocytoma - update on disease management.Case of spontaneous regression of carotid body tumor in a SDHD mutant: a discussion on potential mechanisms based on a review of the literature.Genetics of pheochromocytoma and paraganglioma syndromes: new advances and future treatment options EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma.HRAS mutation prevalence and associated expression patterns in pheochromocytoma.Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas Clinical and genetic investigation of a multi-generational Chinese family afflicted with Von Hippel-Lindau disease Treatment with sunitinib for patients with progressive metastatic pheochromocytomas and sympathetic paragangliomas.Identification of eight novel SDHB, SDHC, SDHD germline variants in Danish pheochromocytoma/paraganglioma patients.Genotype-specific abnormalities in mitochondrial function associate with distinct profiles of energy metabolism and catecholamine content in pheochromocytoma and paraganglioma.Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features.Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling.Phenylethanolamine N-methyltransferase downregulation is associated with malignant pheochromocytoma/paraganglioma.The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas.Integrative genetic characterization and phenotype correlations in pheochromocytoma and paraganglioma tumours.Familial pheochromocytomas and paragangliomas.Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.Global DNA Methylation Analysis Identifies Two Discrete clusters of Pheochromocytoma with Distinct Genomic and Genetic Alterations.From transcriptional profiling to tumor biology in pheochromocytoma and paraganglioma.Pheochromocytoma and paraganglioma: understanding the complexities of the genetic background.

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Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma

http://www.wikidata.org/entity/Q57817523

description

article

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im Juli 2011 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

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наукова стаття, опублікована в липні 2011

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name

Integrative genomic analysis r ...... chromocytoma and paraganglioma

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Integrative genomic analysis r ...... chromocytoma and paraganglioma

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type

label

Integrative genomic analysis r ...... chromocytoma and paraganglioma

@en

Integrative genomic analysis r ...... chromocytoma and paraganglioma

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prefLabel

Integrative genomic analysis r ...... chromocytoma and paraganglioma

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Integrative genomic analysis r ...... chromocytoma and paraganglioma

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Human Molecular Genetics

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Integrative genomic analysis r ...... chromocytoma and paraganglioma

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Annabelle Venisse

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Aurélien de Reynies

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Béatrice Parfait

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Elodie Jouanno

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Ingrid Laurendeau

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Jérôme Bertherat

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Laure Vescovo

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Nelly Burnichon

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Pierre-François Plouin

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Germline mutations in TMEM127 confer susceptibility to pheochromocytoma

A matrix metalloproteinase expressed on the surface of invasive tumour cells

SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

The SDH mutation database: an online resource for succinate dehydrogenase sequence variants involved in pheochromocytoma, paraganglioma and mitochondrial complex II deficiency.

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis.

Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation.

Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes

Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations

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3974-3985

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scholarly article

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10.1093/HMG/DDR324

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20

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20

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Xavier Jeunemaitre

Anne-Paule Gimenez-Roqueplo

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2011-07-22T00:00:00Z

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21784903

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phaeochromocytoma