Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation

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Series of Alkynyl-Substituted Thienopyrimidines as Inhibitors of Protozoan Parasite Proliferation

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 04 September 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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name

Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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P1476

Series of Alkynyl-Substituted ...... otozoan Parasite Proliferation

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Amrita Sharma

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Erica Penn

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Gautam Patel

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Jennifer L Woodring

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Jessey Erath

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Justin Wiedeman

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Kojo Mensa-Wilmot

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Norma Roncal

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Paul Guyett

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Ranjan Behera

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P2860

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases

The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing

Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign

Optimization of topical therapy for Leishmania major localized cutaneous leishmaniasis using a reliable C57BL/6 Model.

New chemical scaffolds for human african trypanosomiasis lead discovery from a screen of tyrosine kinase inhibitor drugs

A new probe for super-resolution imaging of membranes elucidates trafficking pathways

EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.

Target repurposing for neglected diseases.

Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.

Antiparasitic Lead Discovery: Toward Optimization of a Chemotype with Activity Against Multiple Protozoan Parasites.

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996-1001

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scholarly article

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10.1021/ACSMEDCHEMLETT.8B00245

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English

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P478

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P577

2018-09-04T00:00:00Z

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30344906

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6187419

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