Molecular determinants of ginkgolide binding in the glycine receptor pore
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An improved ivermectin-activated chloride channel receptor for inhibiting electrical activity in defined neuronal populationsNeuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation.Ginkgolide B and bilobalide block the pore of the 5-HT₃receptor at a location that overlaps the picrotoxin binding siteBinding sites for bilobalide, diltiazem, ginkgolide, and picrotoxinin at the 5-HT3 receptor.Mechanism of action of the insecticides, lindane and fipronil, on glycine receptor chloride channels.Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptorsWhat single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor.Noncompetitive Inhibition of 5-HT3 Receptors by Citral, Linalool, and Eucalyptol Revealed by Nonlinear Mixed-Effects Modeling.Advantages of an antagonist: bicuculline and other GABA antagonists.Discriminating between 5-HT₃A and 5-HT₃AB receptorsGinkgolic acid specifically potentiates alpha 1 glycine receptors.Ginkgolide X is a potent antagonist of anionic Cys-loop receptors with a unique selectivity profile at glycine receptors.Cys-loop receptor channel blockers also block GLIC.Structure-activity analysis of ginkgolide binding in the glycine receptor pore.Selective potentiation of alpha 1 glycine receptors by ginkgolic acid.Mechanisms for picrotoxinin and picrotin blocks of alpha2 homomeric glycine receptors.Conformational variability of the glycine receptor M2 domain in response to activation by different agonists.Functional Brain Activity Changes after 4 Weeks Supplementation with a Multi-Vitamin/Mineral Combination: A Randomized, Double-Blind, Placebo-Controlled Trial Exploring Functional Magnetic Resonance Imaging and Steady-State Visual Evoked Potentials d
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Molecular determinants of ginkgolide binding in the glycine receptor pore
description
scientific article published on 01 July 2006
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wetenschappelijk artikel
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наукова стаття, опублікована в липні 2006
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name
Molecular determinants of ginkgolide binding in the glycine receptor pore
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Molecular determinants of ginkgolide binding in the glycine receptor pore
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type
label
Molecular determinants of ginkgolide binding in the glycine receptor pore
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Molecular determinants of ginkgolide binding in the glycine receptor pore
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prefLabel
Molecular determinants of ginkgolide binding in the glycine receptor pore
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Molecular determinants of ginkgolide binding in the glycine receptor pore
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P2093
P2860
P1476
Molecular determinants of ginkgolide binding in the glycine receptor pore
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P2093
Hooi-Ling Ng
Joseph W Lynch
Rebecca Hawthorne
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P304
P356
10.1111/J.1471-4159.2006.03875.X
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P577
2006-07-01T00:00:00Z