Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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http://www.wikidata.org/entity/Q58035745

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im Oktober 2018 veröffentlicher wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

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Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

@nl

P1476

Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

@en

P2093

Bart Vanhaesebroeck

http://www.w3.org/2001/XMLSchema#string

P275

Creative Commons Attribution 4.0 International

P2860

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function

Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.

High frequency of mutations of the PIK3CA gene in human cancers

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

Mutational landscape and significance across 12 major cancer types

P304

856-870

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P31

scholarly article

review article

P356

10.1016/J.MOLMED.2018.08.003

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Robert K Semple

Ralitsa R Madsen

P5008

ScienceSource

P577

2018-10-01T00:00:00Z

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P698

30197175

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P921

regulation of gene expression

molecular biology

Anzim

P932

6185869

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