Cyclin E is a more powerful predictor of breast cancer outcome than proliferation

Cyclin E is a more powerful predictor of breast cancer outcome than proliferation

Item
http://www.wikidata.org/entity/Q58188808
Brk is coamplified with ErbB2 to promote proliferation in breast cancerHypoxia-inducible factor 1 is activated by dysregulated cyclin E during mammary epithelial morphogenesis.Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.Cyclin E is stabilized in response to replication fork barriers leading to prolonged S phase arrest.A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels.The extreme COOH terminus of the retinoblastoma tumor suppressor protein pRb is required for phosphorylation on Thr-373 and activation of E2F.The regulation of SIRT2 function by cyclin-dependent kinases affects cell motilityAdenovirus E1B55K region is required to enhance cyclin E expression for efficient viral DNA replication.Skp2 is an independent prognosticator of gallbladder carcinoma among p27(Kip1)-interacting cell cycle regulators: an immunohistochemical study of 62 cases by tissue microarray.Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells.Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment.Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.CCNE1 copy-number gain and overexpression identify ovarian clear cell carcinoma with a poor prognosis.
P2860

Cyclin E is a more powerful predictor of breast cancer outcome than proliferation

Item
http://www.wikidata.org/entity/Q58188808
description
im Februar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 February 2003
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2003
@uk
name
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@en
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@nl
type
label
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@en
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@nl
prefLabel
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@en
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@nl
P1433
P1476
P2093
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
@en
P2093
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P698