about
The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutationsWishing away inflammation? New links between serotonin and TNF signalingMany checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses.Analysis of human immunodeficiency virus cytopathicity by using a new method for quantitating viral dynamics in cell culture.Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome.Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction.The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8.TRAF6 regulates cell fate decisions by inducing caspase 8-dependent apoptosis and the activation of NF-kappaB.Measurement of two caspase activities simultaneously in living cells by a novel dual FRET fluorescent indicator probe.Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse.To B or not to B: TNF family signaling in lymphocytesNatural killer cell expression of Ki67 is associated with elevated serum IL-15, disease activity and nephritis in systemic lupus erythematosusCirculating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF
P50
Q24302236-ACEE170E-229C-4B8C-BACF-30780D8233EAQ24630595-305517C5-7EF8-445B-8A7B-DD8ABC872449Q33672489-4799097C-7AB6-4C5A-91C4-8DD85D41A9E7Q33707384-61E8097D-4293-4924-9AA5-319F7EB6BCCEQ34006517-902B68FC-6483-402C-9909-ED40F0730324Q37541681-5759794B-BBB2-4180-9717-0358241AC414Q39627613-9C6B87C3-A0D9-4ADE-859E-F1F5E1C4A20FQ40325218-744DA160-0617-48B1-B236-C8BECE379029Q50731027-DAEEF6BF-EACF-4670-92FF-8B95D5492D75Q55284675-8A458C04-5DE9-4D3C-BA02-F8CA8A87C0FEQ74108049-7A3E8BFB-810C-4418-933B-39BFC92E5B0EQ91261885-2DE66857-BEB6-411A-9736-00AD6EEB9C7BQ94545262-B46E221B-757B-4D37-9717-082FF3898707
P50
description
researcher, ORCID id # 0000-0001-5953-9893
@en
wetenschapper
@nl
name
Richard M Siegel
@ast
Richard M Siegel
@en
Richard M Siegel
@nl
type
label
Richard M Siegel
@ast
Richard M Siegel
@en
Richard M Siegel
@nl
prefLabel
Richard M Siegel
@ast
Richard M Siegel
@en
Richard M Siegel
@nl
P106
P31
P496
0000-0001-5953-9893