Skeletal Muscle Modulates Huntington's Disease Pathogenesis in Mice: Role of Physical Exercise

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Skeletal Muscle Modulates Huntington's Disease Pathogenesis in Mice: Role of Physical Exercise

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scientific article published on 30 October 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у 2018

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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P1476

Skeletal Muscle Modulates Hunt ...... ice: Role of Physical Exercise

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P2093

Gonzalo Blanco

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P2860

PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease

Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS

PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.

Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's disease

Exercise attenuates neuropathology and has greater benefit on cognitive than motor deficits in the R6/1 Huntington's disease mouse model.

Nuclear translocation of AMPK-alpha1 potentiates striatal neurodegeneration in Huntington's disease.

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

AMPK activation protects from neuronal dysfunction and vulnerability across nematode, cellular and mouse models of Huntington's disease.

Rosiglitazone activation of PPARγ-dependent signaling is neuroprotective in mutant huntingtin expressing cells.

Decreased mRNA expression of PGC-1α and PGC-1α-regulated factors in the SOD1G93A ALS mouse model and in human sporadic ALS.

P304

1179069518809059

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scholarly article

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10.1177/1179069518809059

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P407

English

P478

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P50

Silvia Corrochano

Abraham Acevedo-Arozena

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2018-10-30T00:00:00Z

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P698

30397387

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P921

Huntington disease

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6210627

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