Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

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Physiologically Based Pharmacokinetic Approach to Determine Dosing on Extracorporeal Life Support: Fluconazole in Children on ECMO

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scientific article published on 13 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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name

Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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label

Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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P1476

Physiologically Based Pharmaco ...... luconazole in Children on ECMO

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Andrea N Edginton

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Jeffrey S Barrett

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Kevin M Watt

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Michael Cohen-Wolkowiez

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Michael Sevestre

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Ping Zhao

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P2860

Pharmacokinetic changes during extracorporeal membrane oxygenation: implications for drug therapy of neonates.

Fluconazole dosing for the prevention or treatment of invasive candidiasis in young infants

Plasma concentrations of inflammatory cytokines rise rapidly during ECMO-related SIRS due to the release of preformed stores in the intestine.

Fluconazole MIC and the fluconazole dose/MIC ratio correlate with therapeutic response among patients with candidemia.

Characterization and quantitation of the pharmacodynamics of fluconazole in a neutropenic murine disseminated candidiasis infection model.

Using expression data for quantification of active processes in physiologically based pharmacokinetic modeling.

The pharmacokinetics of fluconazole after a single intravenous dose in AIDS patients.

The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes.

Fluconazole loading dose pharmacokinetics and safety in infants

Pharmacokinetics of vancomycin in critically ill infants undergoing extracorporeal membrane oxygenation.

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629-637

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scholarly article

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10.1002/PSP4.12338

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English

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K L Brouwer

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2018-08-13T00:00:00Z

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30033691

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P921

extracorporeal membrane oxygenation

P932

6202466

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